Results 171 to 180 of about 25,017 (258)

“It's Not Deterministic and It Will Never Be Deterministic”: A Qualitative Study on Stakeholder Perspectives of Polygenic Risk Score Testing for Post‐Traumatic Stress Disorder

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Post‐traumatic stress disorder (PTSD) causes significant mental and physical distress, yet only a small subset of individuals exposed to trauma develop the disorder. Scientists and clinicians are still unable to predict who will get the disorder or how it will manifest.
Brandy M. Fox
wiley   +1 more source

Unravelling the Referendum: An Analysis of the 2023 Australian Voice to Parliament Referendum Outcomes Across Capital Cities

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT The 2023 Australian Voice to Parliament Referendum presented a pivotal moment in the nation's democratic landscape. Despite support for Indigenous well‐being, the referendum did not secure the necessary approval, prompting extensive analysis of its outcome.
Scott Baum, William Mitchell
wiley   +1 more source

Upcycling Water Pollutants Into Long‐Chain Polymers via Synergistic Interfacial Dechlorination and Organic Radical Stabilization

open access: yesAngewandte Chemie, EarlyView.
HEO‐regulated electronic structure drives nonradical PI activation, promoting ETP‐mediated polymerization of 4CP into high‐molecular‐weight products with enhanced surface enrichment. Concurrent dechlorination occurs via radical coupling and •OHads attack, enabling efficient carbon retention and selective product evolution at the liquid–solid interface.
Ziwei Yao   +8 more
wiley   +2 more sources

SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang   +6 more
wiley   +1 more source

Entropy‐Stabilized Aluminate Catalysts That Break the Activity–Stability Tradeoff in CF4 Hydrolysis

open access: yesAngewandte Chemie, EarlyView.
Entropy‐stabilized aluminate breaks the activity–stability tradeoff in CF4 hydrolysis by combining a multication aluminate framework with an entropy‐stabilized lattice. An electron‐deficient Al–O environment is F‐philic but O‐phobic, enabling C–F activation while suppressing H2O poisoning. Under steam‐rich, strongly fluorinating conditions, the entropy‐
Seunghyuck Chi   +7 more
wiley   +2 more sources

Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers

open access: yesAnnals of Neurology, EarlyView.
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang   +45 more
wiley   +1 more source

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