Results 111 to 120 of about 70,920 (305)

Using synthetic rock mass and discrete fracture network approaches to study rock mass strength properties

International audienceIt is widely accepted that fractures decrease the strength of rock masses in comparison to intact rock. This phenomenon is evaluated by rock mass classification systems, such as the Geological Strength Index (GSI).
Lavoine, E., Lavoine, E.,, Darcel, C.,, Ivars, Diego Mas,, Davy, P., Darcel, C., Kasani, H. A.,, Mas Ivars, D., Kasani, H.A., Davy, P.,   +9 more
core   +1 more source

The Shear Strength of Granular Materials with Dispersed and Non-Dispersed Oversized Particles [PDF]

, 2013
Soils containing dispersed and non-dispersed large particles (greater than # 4 sieve) form part of many engineered fills, glacial tills, debris flows, and residual soil deposits.
Seminsky, Leanna
core  

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Influence of the water saturation for the strength of volcanic tuffs

, 2002
Different Hungarian volcanic tuffs (andesite, basalt and rhyolite) were investigated with the goal to determine the influence of the water on their strength.
Vásárhelyi, Balázs
core  

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Spatial Variations of Deformation along a Strike-Slip Fault: A Case Study of Xianshuihe Fault Zone, Southwest China

Applied Sciences
The distribution of damage zones around a fault has long been regarded as a frontier and hot spot in the field of geoscience but is still not fully understood.
Jinxuan Li, Songfeng Guo, Shengwen Qi, Qianhui Wei, Bowen Zheng, Yu Zou, Yongchao Li, Yaguo Zhang, Xiao Lu   +8 more
doaj   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Development of New Three-Dimensional Rock Mass Strength Criteria

, 2018
Two new three-dimensional rock mass strength criteria are developed in this paper by extending an existing rock mass strength criterion. These criteria incorporate the effects of the intermediate principal stress, minimum principal stress and the ...
Xingen, Ma, Kulatilake, Pinnaduwa H.S.W., He, Manchao, Mehranpour, Mohammad Hadi   +3 more
core  

Applications of rock strength borehole probe (RSBP) in underground openings [PDF]

, 2016
ISRM International Symoposium on Rock Mechanics and Rock Engineering - From the Past to the Future -- AUG 29-31, 2016 -- Cappadocia, TURKEYSafe, cost-effective tunnel construction is possible when the ground is stabilized in a reasonable pace.
Keller, E. E., Buyuksagis, I. S., Naeimipour, A., Rostami, J.   +3 more
core  

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source