Results 71 to 80 of about 30,290 (266)

Practical research of free standing rack (Seismic experiment study on full scale free standing rack)

open access: yesNihon Kikai Gakkai ronbunshu, 2015
The spent fuel taken out of a plant reactor is temporarily stored in a spent fuel rack. This fuel will often have to be stored in the rack for long periods before it can be moved to a reprocessing facility. Therefore, the spent fuel rack must have a high
Akihisa IWASAKI   +6 more
doaj   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

open access: yesAdvanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi   +10 more
wiley   +1 more source

Frequency Analysis of Hard Disk Drive Spindle System Supported by Hydrodynamic Bearings

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2007
Herringbone-grooved hydrodynamic bearings are now being applied to hard disk drive (HDD) spindle motors instead of ball bearings for demand for HDDs with larger storage capacities, faster access times, and reduced sizes.
Shohta TOHMA   +5 more
doaj   +1 more source

Mechanotransduction of Magnetically Applied Forces Leads to Mechanical Stiffening of Platelet‐Rich Plugs

open access: yesAdvanced Healthcare Materials, EarlyView.
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia   +4 more
wiley   +1 more source

Sheep Quickstep while the Floor Rock and Rolls: Visuomotor Lateralization during Simulated Sea Travel

open access: yesAnimals, 2019
Unpredictable floor motions during transport disturbs animals’ balance, requiring stepping to move the centre of gravity in the direction of body movement.
Andrew Robins   +4 more
doaj   +1 more source

Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography

open access: yesAdvanced Healthcare Materials, EarlyView.
Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko   +8 more
wiley   +1 more source

Fragility Analysis of Step-Terrace Frame-Energy Dissipating Rocking Wall Structure in Mountain Cities

open access: yesApplied Sciences
Rocking walls can control the overall deformation pattern and the distribution of plastic energy dissipation in structures, suppressing the occurrence of weak layers.
Youfa Yang, Yingwei Jia, Hongshen Jin
doaj   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

open access: yesAdvanced Healthcare Materials, EarlyView.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître   +7 more
wiley   +1 more source

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