Results 191 to 200 of about 6,500 (214)
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Molecular cloning of a rod opsin cDNA from the skate retina
Gene, 1997Skates (Raja erinacea and R. ocellata) are among the few animals that have an exclusively rod retina. However, skate rods are unusual in that they are capable of adapting to extremely high levels of illumination that initially saturate the rod photocurrent.
J, O'Brien, H, Ripps, M R, Al-Ubaidi
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Evolutionarily conserved and divergent regulatory sequences in the fish rod opsin promoter
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2005Fish have multiple types and subtypes of opsin genes that are expressed in a highly regulated manner in retinal photoreceptor cells. In the rod opsin proximal promoter region (RPPR) of zebrafish (Danio rerio), the BAT 1 regulatory region contains highly conserved OTX (GATTA) and OTX-like (TATTA) sequences that can be recognized by the mammalian cone ...
Shoji, Kawamura +4 more
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Mechanism of Transient Dark Activity of 13-Desmethylretinal/Rod Opsin Complex
Journal of the American Chemical Society, 1998We report the studies employing 11-cis-13-desmethylretinal (13dm) 1, its dihydro analogue 2H13dm 2, and 11-cis sixmembered ring-locked analogue ret6 3, to clarify the mechanism of dark activity of the 13-desmethylretinal/rod opsin complex. Rhodopsin (Rh) is composed of a retinal chromophore linked to Lys 296 of the apoprotein opsin via a protonated ...
Qiang Tan +2 more
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Tissue-specific and developmental regulation of rod opsin chimeric genes in transgenic mice
Neuron, 1991Chimeric gene fusions between 4.4 kb of rod opsin 5' flanking sequence fused to a diphtheria toxin gene and 4.4 kb or 500 bp of rod opsin 5' flanking sequence fused to the E. coli IacZ gene were used to generate transgenic mice for analysis of cell type-specific expression and temporal and spatial distribution of reporter gene product during retinal ...
J, Lem +4 more
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all-trans-Retinal Forms a Visible-Absorbing Pigment with Human Rod Opsin
Biochemistry, 2001Rhodopsin activation elicits transmembrane currents due to electrostatic events associated with conformational changes. We employed the sensitive rhodopsin early receptor current approach to reevaluate whether all-trans-retinal can form a visual pigment with rod opsin apoprotein.
L I, Brueggemann, J M, Sullivan
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Immunocytochemical localization of opsin in rod photoreceptors during periods of rapid disc assembly
Journal of Neurocytology, 1995Transport of opsin from photoreceptor inner to outer segments has been assumed to occur via the connecting cilium, the only permanent structural connection between these two regions. However, in prior work, little or no immunoreactive opsin has been detected in the cilium, despite the high rate of transport of this protein.
J C, Besharse, M G, Wetzel
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How the discovery of microbial opsins led to the development of optogenetics
Cell, 2021Jeffrey M Friedman
exaly