Results 51 to 60 of about 882,412 (385)

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

open access: yesNature Communications, 2016
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase-1 (COX-1) and COX-2 enzymes. The NLRP3 inflammasome is a multi-protein complex responsible for the processing of the proinflammatory cytokine interleukin-1β and is implicated in many ...
Michael J. D. Daniels   +24 more
semanticscholar   +1 more source

Neurophysiology of the Developing Cerebral Cortex: What We Have Learned and What We Need to Know

open access: yesFrontiers in Cellular Neuroscience, 2022
This review article aims to give a brief summary on the novel technologies, the challenges, our current understanding, and the open questions in the field of the neurophysiology of the developing cerebral cortex in rodents.
Heiko J. Luhmann
doaj   +1 more source

Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs [PDF]

open access: yes, 2011
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
A. D. Scott   +65 more
core   +2 more sources

Rodent models of AKI-CKD transition.

open access: yesAJP - Renal Physiology, 2018
Acute kidney injury (AKI) is a contributing factor in the development and progression of chronic kidney disease (CKD). Despite rapid progresses, the mechanism underlying AKI-CKD transition remains largely unclear.
Ying Fu   +5 more
semanticscholar   +1 more source

Effects of overgrazing on the functional diversity of rodents in desert areas

open access: yesEcology and Evolution
Environmental stressors and disturbances can cause changes in an ecosystem's community structure, which can be reflected in its functional diversity. As grazing intensity increases, this causes changes in the environment that inevitably lead to changes ...
Na Zhu   +6 more
doaj   +1 more source

Investigating causality with fecal microbiota transplantation in rodents: applications, recommendations and pitfalls

open access: yesGut Microbes, 2021
In recent years, studies investigating the role of the gut microbiota in health and diseases have increased enormously – making it essential to deepen and question the research methodology employed.
Cassandra E. Gheorghe   +5 more
doaj   +1 more source

Towards sustainable management of rodents in organic animal husbandry [PDF]

open access: yes, 2004
From 26 to 28 May 2004 an international seminar was held in Wageningen, the Netherlands, about current knowledge and advice on rodent management on organic pig and poultry farms in Western Europe. This paper summarizes the discussions.
Kijlstra, Aize, Meerburg, Bastiaan
core  

Expression of connexins in human preimplantation embryos in vitro [PDF]

open access: yes, 2004
Intercellular communication via gap junctions is required to coordinate developmental processes in the mammalian embryo. We have investigated if the connexin (Cx) isoforms known to form gap junctions in rodent preimplantation embryos are also expressed ...
Bloor, D.J.   +6 more
core   +4 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Morphometric dataset of Varanus salvator for non-invasive sex identification using machine learning

open access: yesScientific Data
Reliable sex identification in Varanus salvator traditionally relied on invasive methods like genetic analysis or dissection, as less invasive techniques such as hemipenes inversion are unreliable.
Ariff Azlan Alymann   +5 more
doaj   +1 more source

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