Results 201 to 210 of about 9,485,064 (367)

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, EarlyView.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Environmental Housing and Duration of Exposure Affect Striatal Graft Morphology in a Rodent Model of Huntington's Disease [PDF]

, 2008
Máté D. Döbrössy, Stephen B. Dunnett
openalex   +1 more source

Distributed Temporal Coding of Visual Memory Categories in Human Hippocampal Neurons Revealed by an Interpretable Decoding Model

Advanced Science, EarlyView.
This study examines how the human hippocampus encodes visual memory categories. By decoding spiking activity from CA3 and CA1 neurons using an interpretable model, it reveals that category‐specific representations emerge from distributed temporal coding.
Xiwei She, Bryan J. Moore, Brent M. Roeder, George Nune, Brian S. Robinson, Brian Lee, Susan Shaw, Hui Gong, Christianne N. Heck, Gautam Popli, Daniel E. Couture, Adrian W. Laxton, Vasilis Z. Marmarelis, Samuel A. Deadwyler, Charles Liu, Theodore W. Berger, Robert E. Hampson, Dong Song   +17 more
wiley   +1 more source

Development of Evolutionary Gravity Neocognitron Neural Network Model for Behavioral Studies in Rodents

Measurement: Sensors
From the past decades, rodent models have played role in evaluating the use of several drugs for the treatment of brain diseases. Generally, these tests are performed by recoding a video and examine to carry out various annotation about the behavior and ...
Antony Asir Daniel V, Basarikodi K, Suresh S, Nallasivan G, Bhuvanesh A, Milner Paul V   +5 more
doaj  

Hantavirus Infection and Habitat Associations among Rodent Populations in Agroecosystems of Panama: Implications for Human Disease Risk [PDF]

, 2009
Aníbal G. Armién, SangJoon Lee, Mario Ávila, Blas Armién, Publio González, Fernando Gracia, Juan Miguel Pascale, Yaxelis Mendoza, Terry L. Yates, Frederick Koster, Jorge Salazar‐Bravo, Manuel de la Cruz, Brian Hjelle, Yamitzel Zaldívar   +13 more
openalex   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Mapping global risk of bat and rodent borne disease outbreaks to anticipate emerging threats. [PDF]

Sci Rep
Jagadesh S, Cataldo C, Van Bortel W, Van Kleef E, Wint W, Rizzoli A, Busani L, Arsevska E.   +7 more
europepmc   +1 more source

Rodents and quarantinable diseases

, 2001
Sosuke Suzuki
openalex   +2 more sources

Substrain Differences Reveal Novel Disease-Modifying Gene Candidates That Alter the Clinical Course of a Rodent Model of Multiple Sclerosis [PDF]

, 2010
Leslie E. Summers deLuca, Natalia Pikor, Jennifer O’Leary, Georgina Galicia, Lesley A. Ward, Dustin Defreitas, Trisha M. Finlay, Shalina S. Ousman, Lucy R. Osborne, Jennifer L. Gommerman   +9 more
openalex   +1 more source