Programmable scanning diffuse speckle contrast imaging of cerebral blood flow [PDF]
arXivSignificance: Cerebral blood flow (CBF) imaging is crucial for diagnosing cerebrovascular diseases. However, existing large neuroimaging techniques with high cost, low sampling rate, and poor mobility make them unsuitable for continuous and longitudinal CBF monitoring at the bedside.
arxiv
LY503430: Pharmacology, Pharmacokinetics, and Effects in Rodent Models of Parkinson's Disease [PDF]
, 2006 Michael J. O’Neill +5 more
openalex +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
Data Augmentation for Automated Adaptive Rodent Training [PDF]
arXivFully optimized automation of behavioral training protocols for lab animals like rodents has long been a coveted goal for researchers. It is an otherwise labor-intensive and time-consuming process that demands close interaction between the animal and the researcher. In this work, we used a data-driven approach to optimize the way rodents are trained in
arxiv
Rodent Biology and Management; Abstracts of papers presented at the International Conference on Rodent Biology and Management, held at Beijing, China, 5-9 October 1998 [PDF]
Farm Management,
Anonymous +3 more
core +1 more source
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
Advanced Science, EarlyView.The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia +12 more
wiley +1 more source
KPIs 2024 Challenge: Advancing Glomerular Segmentation from Patch- to Slide-Level [PDF]
arXivChronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive benchmarks for kidney pathology segmentation hinders progress in the field. To address this, we organized the Kidney
arxiv
Ectoparasite Diversity and Exposure to Vector-Borne Disease Agents in Wild Rodents in Central Coastal California [PDF]
, 2007 Nathan C. Nieto +7 more
openalex +1 more source
Field methods for rodent studies in Asia and the Indo-Pacific [PDF]
Farm Management,
Aplin, Ken P. +4 more
core +1 more source
Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation
Advanced Science, EarlyView.This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang +6 more
wiley +1 more source