Results 221 to 230 of about 9,520,639 (370)

Epigenetic Regulation of DAPK1 and Netrin‐1 Drives Diabetic Encephalopathy

Advanced Science, EarlyView.
This study identifies a microRNA (miR)‐216a‐5p/death‐associated protein kinase 1 (DAPK1)/hepatocyte nuclear factor 1 homeobox A (HNF1A)/Netrin‐1 signaling axis in diabetic encephalopathy (DE). In leptin receptor‐deficient (db/db) and streptozotocin (STZ)‐induced diabetic mice, reduced miR‐216a‐5p increases DAPK1 expression, disrupting HNF1A binding to ...
Yang Zhou, Jia‐Xin Kou, Kai Zheng, Zi‐Xuan Guo, Hong‐Wei Fan, Wen‐Lian Li, Lu‐Lu Chu, Jing‐Wen Yin, Li‐Jie Liu, Zhi‐Gao Xiang, Feng Hu, Kai Shu, Ling‐Qiang Zhu, Dan Liu   +13 more
wiley   +1 more source

ENVIRONMENTAL CHANGES AND VECTOR AND RODENT BORNE DISEASES IN EUROPE

, 2004
Bettina Menne, Clive R. Davies, Milan Daniel, B Kříž, Normann Gratz   +4 more
openalex   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

Advanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai, Shasha Zhang, Mingchen Dai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Xujun Tang, Wei Tong, Jun He, Qiuyue Mao, Yintao Wang, Zixuan Ye, Tian Wang, Renjie Chai   +14 more
wiley   +1 more source

HIV Protein TAT Dysregulates Multiple Pathways in Human iPSCs-Derived Microglia. [PDF]

Life (Basel)
Guo LL, Jiang R, Cheng Y, Russell B, Yan SY, Guo ML.   +5 more
europepmc   +1 more source

Oxidative stress and pro-apoptotic conditions in a rodent model of Wilson's disease

, 2005
Alberta Samuele, Anna Mangiagalli, Marie‐Thérèse Armentero, Roberto Fancellu, Eleonora Bazzini, Mariapia Vairetti, Andrea Ferrigno, Plinio Richelmi, Giuseppe Nappi, Fabio Blandini   +9 more
openalex   +1 more source

P2‐255: The retina as a window to monitor Alzheimer's disease in human and rodent models: In vivo imaging of retinal Aβ plaques for immunotherapy assessment [PDF]

, 2012
Yosef Koronyo, Brenda Salumbides, Julia Sheyn, Sébastien Fuchs, Robert Cohen, Carol A. Miller, Keith L. Black, Maya Koronyo‐Hamaoui   +7 more
openalex   +1 more source

Animal models of neurodegenerative diseases

Nature Neuroscience, 2018
T. Dawson, T. Golde, C. Lagier-Tourenne
semanticscholar   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

Advanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding, Yuhuan Jia, Lin Liu, Wen Wang, Danxia Zhou, Zheng Zhou, Likun Yang, Xinyi Chen, Di Chen, Yan Mao, Liwei Xiao, Cai‐Zhi Liu, Zhen‐Yu Du, Yujing Yin, Qiqi Guo, Zongchao Sun, Kai Ge, Tingting Fu, Hai‐Long Piao, Zhenji Gan   +19 more
wiley   +1 more source

Virome characterization of field-collected rodents in suburban city. [PDF]

NPJ Biofilms Microbiomes
Hu ZY, Tang F, Zhang MQ, Zhang JT, Zhang YF, Si GQ, Fu BK, Wang G, Li S, Zhang L, Peng C, Ma XF, Liu YT, Su H, Bao PT, Zhang XA, Liu W.   +16 more
europepmc   +1 more source

945. Prevention of Onset of Parkinson's Disease by In Vivo Gene Transfer of Human Hepatocyte Growth Factor in Rodent and Primate Model

, 2005
Hiromi Koike, Akihiko Ishida, Munehisa Shimamura, Naoyuki Sato, Takuya Hayashi, Ryuichi Morishita   +5 more
openalex   +1 more source