Results 221 to 230 of about 9,442,226 (387)
Environmental Housing and Duration of Exposure Affect Striatal Graft Morphology in a Rodent Model of Huntington's Disease [PDF]
Máté D. Döbrössy, Stephen B. Dunnett
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This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo+15 more
wiley +1 more source
Parkinson’s disease: genetic versus toxin‐induced rodent models [PDF]
Mügen Terzioglu, Dagmar Galter
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Japanese encephalitis virus (JEV) employs a cap‐independent (CI) translation strategy to evade host translational shutoff. During the shut‐off of host cellular canonical translation, DEAD‐box protein 3 (DDX3) bind to JEV UTRs to establish a closed‐loop architecture, and its interaction with poly(A)‐binding protein 1 (PABP1) to form DDX3/PABP1/eIF4G ...
Chenxi Li+13 more
wiley +1 more source
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease [PDF]
Diego F. Calvisi+13 more
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Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai+14 more
wiley +1 more source
From the past decades, rodent models have played role in evaluating the use of several drugs for the treatment of brain diseases. Generally, these tests are performed by recoding a video and examine to carry out various annotation about the behavior and ...
Antony Asir Daniel V+5 more
doaj
Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang+9 more
wiley +1 more source
Hantavirus Infection and Habitat Associations among Rodent Populations in Agroecosystems of Panama: Implications for Human Disease Risk [PDF]
Aníbal G. Armién+13 more
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Prevalence, Species Characterization, and Genetic Diversity of <i>Bartonella</i> Infections in Rodents From Mudflat Wetlands Along the Eastern Coast of Jiangsu Province in China. [PDF]
Guoqing C+11 more
europepmc +1 more source