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Endocrine Diseases of Rodents

Veterinary Clinics of North America: Exotic Animal Practice, 2008
The frequency of documented endocrine diseases in rodents and other small mammals varies considerably among the species maintained as pets, biomedical research animals, or display animals in zoos. The clinical diagnosis of endocrine diseases almost never occurs in free-ranging animals in their native habitat.
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Rodent models for human diseases

European Journal of Pharmacology, 2015
One of the factors limiting the translation of knowledge from preclinical studies to the clinic has been the limitations of in vivo diseases models. Except in the case of highly controlled and regulated clinical trials, geneticists and scientists do not use humans for their experimental investigations because of the obvious risk to life.
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Thyroid Diseases in Rodent Species

Veterinary Clinics of North America: Exotic Animal Practice, 2014
There are an abundance of studies of thyroid disease in rodents in a laboratory setting; however, research is limited in pet rodent populations. Validated reference intervals for thyroid testing are scarce, making interpretation of blood work difficult. Hyperthyroidism and hypothyroidism have been reported in multiple rodent species, with the most data
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Fungal diseases of laboratory rodents

Veterinary Clinics of North America: Exotic Animal Practice, 2003
Although fungal disease is uncommon in rodents, dermatophytosis is the most common mycosis seen in clinical practice. T. mentagrophytes is the most common etiologic agent, and the guinea pig is the most common species affected, although there are reports in all pet and laboratory rodent species except the gerbil.
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Rodent and Non-Rodent Animal Models for CardioVascular Diseases

2022
Cardiovascular diseases (CVD) come under non-communicable disease (NCD) that are responsible for the leading cause of death, globally. They involve a range of pathologies viz. coronary artery disease, cerebro-vascular disease, venous thrombo-embolism, peripheral vascular disease, myocardial infarction, cardiac arrhythmias and stroke.
Irfan Ahmad Mir   +4 more
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Promising rodent models in Parkinson's disease

Parkinsonism & Related Disorders, 2018
In the past decade, the study of the pathogenic mechanisms underlying neurodegeneration in Parkinson's disease (PD) has revealed a genetic component, often associated with a number of environmental risk factors. Animal models have improved our understanding of disease pathogenesis, providing significant insights into the understanding of novel ...
Imbriani P.   +4 more
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Skin diseases of rodents

In Practice, 2010
Pet rodents make up a small but significant part of the caseload in small animal veterinary practice. Skin disease is a frequent reason for presentation, as it is easily noticed by the owner, even in species that are not regularly handled. Particular problems encountered with the diagnosis and treatment of skin disease in rodents include the stress of ...
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Genetic Rodent Models of Huntington Disease

2018
The monogenic nature of Huntington disease (HD) has led to the development of a spectrum of useful genetically modified models. In particular, rodents have pioneered as the first HD model being generated and have since been the most widely used animal model for HD in both basic research and preclinical therapeutic studies.
J, Stricker-Shaver   +3 more
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Thyroid Disease in Rabbits and Rodents

Veterinary Clinics of North America: Exotic Animal Practice
While thyroid disease is generally uncommon in rabbits and rodents, it is most frequently diagnosed in guinea pigs. Particularly, hyperthyroidism and thyroid neoplasms are diagnosed regularly in this species, while thyroid neoplasia is the most common thyroid disorder found in other rodents.
Milena, Thöle, Tina, Brezina
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Infectious respiratory disease in rodents

In Practice, 2004
MOST of the current knowledge regarding respiratory disease in rodents is based on the management of laboratory rodents. The emphasis is on diagnosis, elimination and prevention of subclinical respiratory disease rather than treatment. In the author's experience, rats are the most frequently presented small mammals with respiratory problems, followed ...
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