Results 261 to 270 of about 341,043 (301)
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Rodent models of genetic disease
Current Opinion in Genetics & Development, 2003The genetic study of rats and mice using natural variants, natural mutations, chemical or radiation induced mutations, engineered mutations and conditional engineered mutations has provided the tools for investigating the genetics of disease. The completion of the mouse genomic sequence and progress towards sequencing the rat genome in the past year ...
Roger D, Cox, Steve D M, Brown
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Rodent models for Alzheimer disease
Nature Reviews Neuroscience, 2018Animal models are indispensable tools for Alzheimer disease (AD) research. Over the course of more than two decades, an increasing number of complementary rodent models has been generated. These models have facilitated testing hypotheses about the aetiology and progression of AD, dissecting the associated pathomechanisms and validating therapeutic ...
Jürgen Götz +2 more
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Veterinary Clinics of North America: Exotic Animal Practice, 2008
The frequency of documented endocrine diseases in rodents and other small mammals varies considerably among the species maintained as pets, biomedical research animals, or display animals in zoos. The clinical diagnosis of endocrine diseases almost never occurs in free-ranging animals in their native habitat.
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The frequency of documented endocrine diseases in rodents and other small mammals varies considerably among the species maintained as pets, biomedical research animals, or display animals in zoos. The clinical diagnosis of endocrine diseases almost never occurs in free-ranging animals in their native habitat.
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Rodent and Non-Rodent Animal Models for CardioVascular Diseases
2022Cardiovascular diseases (CVD) come under non-communicable disease (NCD) that are responsible for the leading cause of death, globally. They involve a range of pathologies viz. coronary artery disease, cerebro-vascular disease, venous thrombo-embolism, peripheral vascular disease, myocardial infarction, cardiac arrhythmias and stroke.
Irfan Ahmad Mir +4 more
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Journal of Veterinary Dentistry, 1990
The dental diseases of rodents are unique because of their dental anatomy and physiology. Common problems of rodent dentitions are covered in this article including periodontal disease, stomatitis, caries, and malocclusions. The anatomy of rodent dentitions is reviewed. Treatment for these diseases is included.
Robert B. Wiggs, Heidi B. Lobprise
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The dental diseases of rodents are unique because of their dental anatomy and physiology. Common problems of rodent dentitions are covered in this article including periodontal disease, stomatitis, caries, and malocclusions. The anatomy of rodent dentitions is reviewed. Treatment for these diseases is included.
Robert B. Wiggs, Heidi B. Lobprise
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Thyroid Disease in Rabbits and Rodents
Veterinary Clinics of North America: Exotic Animal PracticeWhile thyroid disease is generally uncommon in rabbits and rodents, it is most frequently diagnosed in guinea pigs. Particularly, hyperthyroidism and thyroid neoplasms are diagnosed regularly in this species, while thyroid neoplasia is the most common thyroid disorder found in other rodents.
Milena, Thöle, Tina, Brezina
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Fungal diseases of laboratory rodents
Veterinary Clinics of North America: Exotic Animal Practice, 2003Although fungal disease is uncommon in rodents, dermatophytosis is the most common mycosis seen in clinical practice. T. mentagrophytes is the most common etiologic agent, and the guinea pig is the most common species affected, although there are reports in all pet and laboratory rodent species except the gerbil.
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Thyroid Diseases in Rodent Species
Veterinary Clinics of North America: Exotic Animal Practice, 2014There are an abundance of studies of thyroid disease in rodents in a laboratory setting; however, research is limited in pet rodent populations. Validated reference intervals for thyroid testing are scarce, making interpretation of blood work difficult. Hyperthyroidism and hypothyroidism have been reported in multiple rodent species, with the most data
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Parkinson’s disease: a rethink of rodent models
Experimental Brain Research, 2006Parkinson's disease (PD) is a multifactorial disease with a complex etiology that results from genetic risk factors, environmental exposures and most likely a combination of both. Rodent models of parkinsonism aim to reproduce key pathogenic features of the syndrome including movement disorder induced by the progressive loss of dopaminergic neurons in ...
Heather L, Melrose +3 more
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Promising rodent models in Parkinson's disease
Parkinsonism & Related Disorders, 2018In the past decade, the study of the pathogenic mechanisms underlying neurodegeneration in Parkinson's disease (PD) has revealed a genetic component, often associated with a number of environmental risk factors. Animal models have improved our understanding of disease pathogenesis, providing significant insights into the understanding of novel ...
Imbriani P. +4 more
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