Results 41 to 50 of about 203,814 (292)

Respiratory Diseases of Rodents and Rabbits

Veterinary Clinics of North America: Small Animal Practice, 2000
This article is written to provide differential diagnostic help for the practitioner who suspects respiratory disease in rodents or rabbits. The authors are laboratory animal veterinarians who work with rodents and rabbits on a herd health basis but also have considerable experience dealing with individual mice, rats, guinea pigs, hamsters, gerbils ...
Langan, George P., Lohmiller, Jeffrey J., Swing, Sonya P., Wardrip, Craig L.   +3 more
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Metagenomic analysis of viromes in tissues of wild Qinghai vole from the eastern Tibetan Plateau

Scientific Reports, 2022
Rodents are natural reservoirs of diverse zoonotic viruses and widely distributed on the Tibetan Plateau. A comprehensive understanding of the virome in local rodent species could provide baseline of viral content and assist in efforts to reduce the risk
Xiaozhou He, Xu Wang, Guohao Fan, Fan Li, Weiping Wu, Zhenghuan Wang, Meihua Fu, Xu Wei, Shuo Ma, Xuejun Ma   +9 more
doaj   +1 more source

Animal Models of Metabolic Disorders in the Study of Neurodegenerative Diseases: An Overview

Frontiers in Neuroscience, 2021
The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the sporadic forms of Alzheimer’s and Parkinson’s disease—are increasing worldwide.
Andreza Fabro de Bem, Rachel Krolow, Hémelin Resende Farias, Victória Linden de Rezende, Daniel Pens Gelain, José Cláudio Fonseca Moreira, João Miguel das Neves Duarte, João Miguel das Neves Duarte, Jade de Oliveira   +8 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

PIODERMITE PROFUNDA POR Corynebacterium pseudotuberculosis EM CUTIA (Dasyprocta sp.)

Ciência Animal Brasileira, 2010
Bacterial skin diseases represent a significant ratio ofrodents’ pathologies. However, in agoutis (Dasyprocta sp.), amiddle-sized rodent with geographic distribution from Central toSouth America, reports on isolated bacterial agents of ...
Kilder Dantas Filgueira, Moacir Franco de Oliveira, Jael Soares Batista, Francisco Marlon Carneiro Feijó, Valéria Veras de Paula   +4 more
doaj  

Use of large animal models to investigate Huntington's diseases

Cell Regeneration, 2019
Animal models that can mimic human diseases are the important tools for investigating the pathogenesis of the diseases and finding a way for treatment.
Sen Yan, Shihua Li, Xiao-Jiang Li
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Knowledge, risk perceptions and practices regarding rodents and their associated pathogens: environmental consultants in Chile

One Health Outlook
Background Rodents play essential ecological roles but are also significant reservoirs of zoonotic pathogens, posing risks to humans. Individuals with frequent occupational contact with rodents face an elevated risk of exposure to rodent-borne diseases ...
Esteban Vásquez, Rodrigo Salgado, Hugo Mendoza, Diego A. Peñaranda, Darío Moreira-Arce, André V. Rubio   +5 more
doaj   +1 more source