Results 71 to 80 of about 9,442,226 (387)

A Remote Monitoring System for Rodent Infestation Based on LoRaWAN

open access: yesSensors, 2023
Rodent infestations are a common problem that can result in several issues, including diseases, damage to property, and crop loss. Conventional methods of controlling rodent infestations often involve using mousetraps and applying rodenticides manually ...
Shin-Chi Lai   +3 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Metagenomic analysis of viromes in tissues of wild Qinghai vole from the eastern Tibetan Plateau

open access: yesScientific Reports, 2022
Rodents are natural reservoirs of diverse zoonotic viruses and widely distributed on the Tibetan Plateau. A comprehensive understanding of the virome in local rodent species could provide baseline of viral content and assist in efforts to reduce the risk
Xiaozhou He   +9 more
doaj   +1 more source

Animal Models of Metabolic Disorders in the Study of Neurodegenerative Diseases: An Overview

open access: yesFrontiers in Neuroscience, 2021
The incidence of metabolic disorders, as well as of neurodegenerative diseases—mainly the sporadic forms of Alzheimer’s and Parkinson’s disease—are increasing worldwide.
Andreza Fabro de Bem   +8 more
doaj   +1 more source

Muti-view Mouse Social Behaviour Recognition with Deep Graphical Model [PDF]

open access: yes, 2020
Home-cage social behaviour analysis of mice is an invaluable tool to assess therapeutic efficacy of neurodegenerative diseases. Despite tremendous efforts made within the research community, single-camera video recordings are mainly used for such analysis.
arxiv   +1 more source

Rodent models in neuroscience research: is it a rat race?

open access: yesDisease Models & Mechanisms, 2016
Rodents (especially Mus musculus and Rattus norvegicus) have been the most widely used models in biomedical research for many years. A notable shift has taken place over the last two decades, with mice taking a more and more prominent role in biomedical ...
B. Ellenbroek, J. Youn
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Application of Superpixels to Segment Several Landmarks in Running Rodents [PDF]

open access: yes, 2018
Examining locomotion has improved our basic understanding of motor control and aided in treating motor impairment. Mice and rats are the model system of choice for basic neuroscience studies of human disease. High frame rates are needed to quantify the kinematics of running rodents, due to their high stride frequency.
arxiv   +1 more source

Pain pathogenesis in rheumatoid arthritis -- what have we learned from animal models [PDF]

open access: yesPAIN 2018 Sep; 159 Suppl:S98-S109, 2019
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by joint inflammation and joint pain. Much of RA treatment is focused on suppressing inflammation, with the idea being that if inflammation is controlled other symptoms, such as pain, will disappear. However, pain is the most common complaint of RA patients, is often still present
arxiv   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

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