HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim+9 more
wiley +1 more source
Geographic distribution of Orientia tsutsugamushi strains on chigger mites in the Republic of Korea (2021-2023). [PDF]
Lee HS, Noh BE, Kim H, Lee H.
europepmc +1 more source
Investigating Geometric Representation in Rodents [PDF]
Arsenault, Samantha Ann
core +2 more sources
Remarks on Finsen's Light Treatment of Lupus and Rodent Ulcer [PDF]
Manfred Morris, S. E. Dore
openalex +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source
Molecular and Serological Detection of Toxoplasma gondii in Two Species of Rodents: Ctenodactylus gundi (Rodentia, Ctenodactylidae) and Psammomys obesus (Rodentia, Muridae) From South Tunisia. [PDF]
Bouaicha F+6 more
europepmc +1 more source
Differentiation in the Rodent Ulcer Group of Tumours
Bernard Lennox, Alan Wells
openalex +2 more sources
Case Shown as Multiple Rodent Ulcer or (?) Epithelioma Adenoides Cysticum [PDF]
E. G. Graham Little
openalex +1 more source
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee+5 more
wiley +1 more source
Rodent Seed Dispersal Syndromes Follow a Downslope Trajectory, Counteracting the Climate Change-Mediated Tree Line Elevational Shift Upwards. [PDF]
Han N+6 more
europepmc +1 more source