Results 231 to 240 of about 2,506,343 (333)

Selecting an appropriate stress model of depression in rodents. [PDF]

World J Psychiatry
Lu XX, Tang H, Li XH.
europepmc   +1 more source

Hair Follicle Regeneration Using Grafted Rodent and Human Cells [PDF]

, 2007
Ritsuko Ehama, Yumiko Ishimatsu‐Tsuji, Shunsuke Iriyama, Ritsuro Ideta, Tsutomu Soma, Kiichiro Yano, Chikako Kawasaki, Satoshi Suzuki, Yuji Shirakata, Koji Hashimoto, Jiro Kishimoto   +10 more
openalex   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

The Map's Design: Evolution's Impact on Navigation and Spatial Cognition. [PDF]

Animals (Basel)
Olynik-McLaughlin IS, Marrone DF.
europepmc   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

The prevalence and genetic diversity of Bartonella species in wild rodents from South Korea. [PDF]

Sci Rep
Kim Y, Lee GS, Lee MG, Park JS, Kim KG, Yang SJ, Lee JE, Kim E, Seo JM, Jung B, Kim SH, Moon C.   +11 more
europepmc   +1 more source

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

Advanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim, Ji‐Young Yoon, Hwalim Lee, Shanika Karunasagara, Cheng Ji Li, Yongdae Shin, Sukbum Hong, Dong‐Joon Lee, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +10 more
wiley   +1 more source

Seasonal and biological drivers of gastrointestinal parasites in wild rodents from two areas with different anthropogenic pressures in a semi-arid region. [PDF]

BMC Vet Res
Carrera-Játiva PD, Verdugo C, Landaeta-Aqueveque C, Peña-Espinoza M, Acosta-Jamett G.   +4 more
europepmc   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Functional Traits Shape Seed-Rodent Interactions in a Subtropical Forest: Insights From Individual-Based Tracking With Double-Duplex PIT Tagging. [PDF]

Ecol Evol
Gu H, Yang X, Dirzo R, Zhang Z.
europepmc   +1 more source