Results 31 to 40 of about 2,707,765 (379)

PEBP balances apoptosis and autophagy in whitefly upon arbovirus infection

Nature Communications, 2022
Arbovirus has co-evolved with its insect vector, enabling efficient and persistent transmission by vectors. Here, the authors reveal an immune homeostatic mechanism shaped by apoptosis and autophagy that facilitates arbovirus preservation within its ...
Shifan Wang, Huijuan Guo, Keyan Zhu-Salzman, Feng Ge, Yucheng Sun   +4 more
doaj   +1 more source

The invasion process of the entomopathogenic fungus Ophiocordyceps sinensis into the larvae of ghost moths (Thitarodes xiaojinensis) using a GFP-labeled strain

Frontiers in Microbiology, 2022
Chinese cordyceps is a well-known and valuable traditional Chinese medicine that forms after Ophiocordyceps sinensis parasitizes ghost moth larvae. The low natural infection rate of O.
Peipei Wu, Peipei Wu, Qilian Qin, Jihong Zhang, Huan Zhang, Xuan Li, Hongtuo Wang, Qian Meng   +7 more
doaj   +1 more source

Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness [PDF]

, 2014
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen activated protein kinases (MAPK)
Bal, Elisa Dora, Barreiro, Eshter, Chacon Cabrera, Alba, Diament, Miriam, Fermoselle, Clara, Mateu Jimenez, Mercè, Sandri, Marco, Urtreger, Alejandro Jorge   +7 more
core   +1 more source

N-glycosylation of Viral E Protein Is the Determinant for Vector Midgut Invasion by Flaviviruses

mBio, 2018
Transmission of flaviviruses by hematophagous insects such as mosquitoes requires acquisition of the virus during blood feeding on the host, with midgut as the primary infection site.
Dan Wen, Suhua Li, Fangfang Dong, Yanan Zhang, Yongfang Lin, Jumei Wang, Zhen Zou, Aihua Zheng   +7 more
doaj   +1 more source

A Plant Virus Ensures Viral Stability in the Hemolymph of Vector Insects through Suppressing Prophenoloxidase Activation

mBio, 2020
Most plant viruses require vector insects for transmission. Viral stability in the hemolymph of vector insects is a prerequisite for successful transmission of persistent plant viruses.
Xiaofang Chen, Jinting Yu, Wei Wang, Hong Lu, Le Kang, Feng Cui   +5 more
doaj   +1 more source

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice [PDF]

, 2016
The FDA approved drug rapamycin increases lifespan in rodents and delays age-related dysfunction in rodents and humans. Nevertheless, important questions remain regarding the optimal dose, duration, and mechanisms of action in the context of healthy ...
Anderson, Anisimov, Atarashi, Augustine, Bates, Blackwell, Chen, Dai, de Oliveira, Ericsson, Ericsson, Flynn, Goldman, Halloran, Hard, Harrison, Hothorn, Johnson, Johnson, Johnson, Kaeberlein, Lamming, Majumder, Mannick, Mathew, Miller, Miller, Paulson, Prakash, Ramos, Treuting, Wilkinson, Xu, Zhang   +33 more
core   +1 more source

Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats [PDF]

, 2011
The protozoan parasite Toxoplasma gondii is prevalent worldwide and can infect a remarkably wide range of hosts despite felids being the only definitive host.
A. P. COX, D. THOMASSON, Dubey, Dubey, E. A. WRIGHT, Franti, G. HIDE, Hejlicek, Hide, J. M. HUGHES, Jacobs, K. BOYCE, M. ABUSHAHMA, M. T. ROGAN, N. S. DODD, O. GERWASH, R. G. MURPHY, Z.-R. LUN   +17 more
core   +2 more sources

Modeling Autistic Features in Animals [PDF]

, 2011
A variety of features of autism can be simulated in rodents, including the core behavioral hallmarks of stereotyped and repetitive behaviors, and deficits in social interaction and communication.
Patterson, Paul H.
core   +1 more source

The Role of RFamide-Related Peptide-3 in Age-Related Reproductive Decline in Female Rats. [PDF]

, 2016
Reproductive senescence, the point in time when females cease to show estrous cyclicity, is associated with endocrine changes in the hypothalamus, pituitary, and gonads. However, the mechanisms triggering this transition are not well understood.
Bentley, George E, Geraghty, Anna C, Kaufer, Daniela, Kriegsfeld, Lance J, Muroy, Sandra E   +4 more
core   +1 more source

Influence of HFD-induced precocious puberty on neurodevelopment in mice

Nutrition & Metabolism, 2021
Background Precocious puberty is frequently associated with obesity, which will lead to long-term effects, especially on growth and reproduction. However, the effect of precocious puberty on children's neurodevelopment is still unknown.
Tingbei Bo, Jing Wen, Wenting Gao, Liqiu Tang, Min Liu, Dehua Wang   +5 more
doaj   +1 more source