Results 41 to 50 of about 2,472,951 (282)
Ecology and Evolution, 2022 A mating system is an important life history for animals dealing with changing environments. Population density affects the plasticity of a mating system and subsequently the family structure of animals, but its impacts on mating systems and social ...
Erdenetuya Batsuren +7 more
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Mammalian pest problems in organic pig farming, preventive measures and control [PDF]
, 2003 Organic pig farming includes having pigs in open fields with relatively close contact to the wild fauna. The risk of transmission of parasites and diseases to the pigs is therefore higher than in traditional pig farming with pigs under strict control in ...
Knorr, M., Leirs, H., Lodal, J.
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
BMC BiologyBackground Mosquitoes transmit many infectious diseases that affect human health. The fungus Beauveria bassiana is a biological pesticide that is pathogenic to mosquitoes but harmless to the environment.
Tengfei Lu +5 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
GAF-dependent chromatin plasticity determines promoter usage to mediate locust gregarious behavior
The EMBO JournalLocusts, as devastating pests, can reversibly transform between solitary individuals and gregarious swarms with markedly different behaviors. Epigenetic regulation orchestrated by changes in chromatin openness modulates behavioral plasticity by ...
Xiao Li +7 more
doaj +1 more source
Dop1 enhances conspecific olfactory attraction by inhibiting miR-9a maturation in locusts
Nature Communications, 2018 Migratory locusts shift between aggregating together during gregarious phases and living individually during solitary phases. Here, the authors find that the D1-like dopamine receptor regulates the olfactory attraction underlying this behavioral switch ...
Xiaojiao Guo +7 more
doaj +1 more source
Two predominant MUPs, OBP3 and MUP13, are male pheromones in rats
Frontiers in Zoology, 2018 Background In rats, urine-borne male pheromones comprise organic volatile compounds and major urinary proteins (MUPs). A number of volatile pheromones have been reported, but no MUP pheromones have been identified in rat urine.
Xiao Guo +4 more
doaj +1 more source
Total orthotopic small bowel transplantation in swine under FK 506 [PDF]
, 1994 Previous experimental studies in rodents and in dogs have established the efficacy of FK 506 in controlling the immunologic events following small bowel or multivisceral transplantation.1–5 To complete the assessment of FK 506 in experimental small bowel
Alessiani, M +14 more
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The Role of RFamide-Related Peptide-3 in Age-Related Reproductive Decline in Female Rats. [PDF]
, 2016 Reproductive senescence, the point in time when females cease to show estrous cyclicity, is associated with endocrine changes in the hypothalamus, pituitary, and gonads. However, the mechanisms triggering this transition are not well understood.
Bentley, George E +4 more
core +1 more source