Results 61 to 70 of about 102,516 (255)

RODENTS AS A FOOD SOURCE [PDF]

, 1990
Rodents, one of several kinds of vertebrates included in the human diet, are very suitable as human food. More than 71 genera and 89 species of rodents, mostly hystricomorphs, have been consumed by man.
Fiedler, Lynwood A.
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The c-Jun N-terminal kinase pathway of a vector insect is activated by virus capsid protein and promotes viral replication

eLife, 2017
No evidence has shown whether insect-borne viruses manipulate the c-Jun N-terminal kinase (JNK) signaling pathway of vector insects. Using a system comprising the plant virus Rice stripe virus (RSV) and its vector insect, the small brown planthopper, we ...
Wei Wang, Wan Zhao, Jing Li, Lan Luo, Le Kang, Feng Cui   +5 more
doaj   +1 more source

Molecular epidemiology of paramyxoviruses in Zambian wild rodents and shrews [PDF]

, 2014
Rodents and shrews are known to harbour various viruses. Paramyxoviruses have been isolated from Asian and Australian rodents, but little is known about them in African rodents.
Mweene, Aaron S., Ishii, Akihiro, Thomas, Yuka, Orba, Yasuko, Hang'ombe, Bernard M., Kimura, Takashi, Moonga, Ladslav, Sawa, Hirofumi, Muleya, Walter, Sasaki, Michihito   +9 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

An iron-binding protein of entomopathogenic fungus suppresses the proliferation of host symbiotic bacteria

Microbiome
Background Entomopathogenic fungal infection-induced dysbiosis of host microbiota offers a window into understanding the complex interactions between pathogenic fungi and host symbionts.
Juan Li, Jiujie Li, Lili Cao, Qinghua Chen, Ding Ding, Le Kang   +5 more
doaj   +1 more source

Correction to: Huddling remodels gut microbiota to reduce energy requirements in a small mammal species during cold exposure

Microbiome, 2018
Following publication of the original article [1], the authors reported an error in the caption of Fig. 4.
Xue-Ying Zhang, Gansukh Sukhchuluun, Ting-Bei Bo, Qing-Sheng Chi, Jun-Jie Yang, Bin Chen, Lei Zhang, De-Hua Wang   +7 more
doaj   +1 more source

THE TREATMENT OF RODENT ULCER [PDF]

BMJ, 1911
n ...
openaire   +3 more sources

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source