Results 71 to 80 of about 2,726,823 (350)

Risk factors for human acute leptospirosis in northern Tanzania [PDF]

, 2018
Introduction: Leptospirosis is a major cause of febrile illness in Africa but little is known about risk factors for human infection. We conducted a cross-sectional study to investigate risk factors for acute leptospirosis and Leptospira ...
Allan, Kathryn J., Biggs, Holly M., Cash-Goldwasser, Shama, Cleaveland, Sarah, Crump, John A., Galloway, Renee L., Halliday, Jo E.B., Kazwala, Rudovick R., Lwezaula, Bingileki F., Maro, Venance P., Maze, Michael J., Mmbaga, Blandina T., Muiruri, Charles, Rubach, Matthew P., Saganda, Wilbrod, Shand, Michael C., Sharples, Katrina J.   +16 more
core   +2 more sources

Behavioral methods to study anxiety in rodents

Dialogues in Clinical Neuroscience, 2017
Stress is a precipitating factor for anxiety-related disorders, which are among the leading forms of psychiatric illness and impairment in the modern world.
K. R. Lezak, G. Missig, W. A. Carlezon Jr.   +2 more
semanticscholar   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Subchronic Exposure to Low-Dose Chlorfenapyr and Emamectin Benzoate Disrupts Kidney Metabolism in Rats

Toxics
Residues of the pesticides chlorfenapyr (CFP) and emamectin benzoate (EMB) often coexist in the environment and can be accumulated in the body. To understand the impact of these two chemicals on health, we investigated their effect on the kidneys.
Di Zhang, Xiao-Hua Song, Dan Yang, Mu-Zi Ge, Jun Qiu, Han-Qing Jiang, Yan-Yan Sun, Xiang-dong Li, Yi-Jun Wu   +8 more
doaj   +1 more source

Rice stripe virus-derived siRNAs play different regulatory roles in rice and in the insect vector Laodelphax striatellus

BMC Plant Biology, 2018
Background Most plant viruses depend on vector insects for transmission. Upon viral infection, virus-derived small interfering RNAs (vsiRNAs) can target both viral and host transcripts.
Meiling Yang, Zhongtian Xu, Wan Zhao, Qing Liu, Qiong Li, Lu Lu, Renyi Liu, Xiaoming Zhang, Feng Cui   +8 more
doaj   +1 more source

Microhabitat Governs the Microbiota of the Pinewood Nematode and Its Vector Beetle: Implication for the Prevalence of Pine Wilt Disease

Microbiology Spectrum, 2022
Our understanding of environmental acquisition of microbes and migration-related alteration of microbiota across habitats has rapidly increased. However, in complex life cycles, such as for many parasites, exactly how these microbes are transmitted ...
Haokai Tian, Lilin Zhao, Tuuli-Marjaana Koski, Jianghua Sun   +3 more
doaj   +1 more source

Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health [PDF]

, 2017
Daily interactions between the hypothalamic circadian clock at the suprachiasmatic nucleus (SCN) and peripheral circadian oscillators regulate physiology and metabolism to set temporal variations in homeostatic regulation.
Diego A. Golombek, Juan J. Chiesa, Leandro P. Casiraghi, Natalia Paladino, Paula García Moro, Santiago A. Plano, Santiago A. Plano   +6 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A double-agent microRNA regulates viral cross-kingdom infection in animals and plants

The EMBO Journal
Plant arbovirus infection is regulated by a delicate interplay between virus, vector, and host. While microRNAs are known to be transmitted across species, their role as cross-kingdom effectors in influencing arbovirus infectious cycles remains poorly ...
Wan Zhao, Hong, Lu, Jiaming Zhu, Lan Luo, Feng Cui   +4 more
doaj   +1 more source

Calomys callosus: An Experimental Animal Model Applied to Parasitic Diseases Investigations of Public Health Concern

Pathogens, 2022
The appearance and spread of parasitic diseases around the world aroused the interest of the scientific community to discover new animal models for improving the quality and specificity of surveys. Calomys callosus is a rodent native to South America, an
Rafael Borges Rosa, Mylla Spirandelli da Costa, Samuel Cota Teixeira, Emilene Ferreira de Castro, Willyenne Marília Dantas, Eloisa Amália Vieira Ferro, Murilo Vieira da Silva   +6 more
doaj   +1 more source