Results 81 to 90 of about 2,707,765 (379)

CRISPR/Cas9-mediated genome editing induces exon skipping by complete or stochastic altering splicing in the migratory locust

open access: yesBMC Biotechnology, 2018
Background The CRISPR/Cas9 system has been widely used to generate gene knockout/knockin models by inducing frameshift mutants in cell lines and organisms.
Dafeng Chen   +5 more
doaj   +1 more source

Microhabitat Governs the Microbiota of the Pinewood Nematode and Its Vector Beetle: Implication for the Prevalence of Pine Wilt Disease

open access: yesMicrobiology Spectrum, 2022
Our understanding of environmental acquisition of microbes and migration-related alteration of microbiota across habitats has rapidly increased. However, in complex life cycles, such as for many parasites, exactly how these microbes are transmitted ...
Haokai Tian   +3 more
doaj   +1 more source

Role of rodents in transmission of Salmonella and Campylobacter [PDF]

open access: yes, 2007
Salmonella and Campylobacter are generally regarded as the most important food-borne pathogens in the world. Reduction or elimination of these pathogens in the first part of the food chain (on the farm) is important to prevent disease among consumers of ...
Kijlstra, Prof dr A, Meerburg, Dr BG
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Calomys callosus: An Experimental Animal Model Applied to Parasitic Diseases Investigations of Public Health Concern

open access: yesPathogens, 2022
The appearance and spread of parasitic diseases around the world aroused the interest of the scientific community to discover new animal models for improving the quality and specificity of surveys. Calomys callosus is a rodent native to South America, an
Rafael Borges Rosa   +6 more
doaj   +1 more source

Diffusion and Home Range Parameters from Rodent Population Measurements in Panama

open access: yes, 2005
Simple random walk considerations are used to interpret rodent population data collected in Hantavirus-related investigations in Panama regarding the short-tailed cane mouse, \emph{Zygodontomys brevicauda}.
Abramson, G.   +5 more
core   +2 more sources

Dispersal and population structure at different spatial scales in the subterranean rodent Ctenomys australis [PDF]

open access: yes, 2010
This study was funded by grants from Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET, PIP5838), Agencia de Promoción Científica y Tecnológica de la Argentina (PICTO1-423, BID-1728/OC-AR), and the programme ECOS-Sud France/Argentina ...
Gaggiotti, Oscar E.   +4 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

The c-Jun N-terminal kinase pathway of a vector insect is activated by virus capsid protein and promotes viral replication

open access: yeseLife, 2017
No evidence has shown whether insect-borne viruses manipulate the c-Jun N-terminal kinase (JNK) signaling pathway of vector insects. Using a system comprising the plant virus Rice stripe virus (RSV) and its vector insect, the small brown planthopper, we ...
Wei Wang   +5 more
doaj   +1 more source

Presence of Salmonella and Campylobacter spp. in Wild Small Mammals on Organic Farms [PDF]

open access: yes, 2005
The presence of Salmonella and Campylobacter spp. in rodents and insectivores (n 282) was investigated on organic farms. Infections were encountered in house mice (8 of 83 Campylobacter positive and 1 of 83 Salmonella sp.
B. G., Meerburg, W. F., Jacobs-Reitsma
core  

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