Results 81 to 90 of about 2,659,769 (337)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Preparation and characterisation of food grade chitosan from housefly larvae

open access: yesCzech Journal of Food Sciences, 2011
The preparation and characterisation of food-grade chitosan from housefly larvae are reported. A refinement procedure was developed to remove larval mouth hooks from the primary chitosan product, which greatly improved the quality of the final product ...
Ai-Jun Zhang   +6 more
doaj   +1 more source

Gut Microbiota and Host Thermoregulation in Response to Ambient Temperature Fluctuations

open access: yesmSystems, 2020
Ambient temperature (Ta) is an important factor in shaping phenotypic plasticity. Plasticity is generally beneficial for animals in adapting to their environments.
Saeid Khakisahneh   +3 more
doaj   +1 more source

Studies on the toxicity of Vacor (RH-787) on the reproductive biology of Rattus rattus rufescens [PDF]

open access: yes, 1980
Vacor (RH-787), a relatively new rodenticide, was evaluated for the control of Rattus rattus rufescens. The symptoms of paralysis in hind limbs were observed after feeding it to rodents.
Saxena, Y., Sharma, P. P., Zutshi, M.
core  

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan   +46 more
wiley   +1 more source

Rodent models for the analysis of tissue clock function in metabolic rhythms research [PDF]

open access: yes, 2017
The circadian timing system consists on a distributed network of cellular clocks that together coordinate 24-h rhythms of physiology and behavior. Clock function and metabolism are tightly coupled, from the cellular to the organismal level.
Astiz, Mariana   +3 more
core   +2 more sources

Domestic cats and dogs create a landscape of fear for pest rodents around rural homesteads

open access: yesPLoS ONE, 2017
Using domestic predators such as cats to control rodent pest problems around farms and homesteads is common across the world. However, practical scientific evidence on the impact of such biological control in agricultural settings is often lacking.
T. Mahlaba   +3 more
semanticscholar   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann   +6 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan   +22 more
wiley   +1 more source

Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome

open access: yesAdvanced Biology, EarlyView.
This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.
Bokyong Kim   +11 more
wiley   +1 more source

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