Results 111 to 120 of about 6,987,443 (300)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
This chapter traces the history of tabletop role-playing games (TRPGs). It treats Dungeons & Dragons (D&D) as a key textual expression of TRPG experience with which other designs and play communities are in dialogue but which itself changes over ...
Torner, Evan +5 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Broadcast culture meets role-playing culture [Elektronisk resurs]
, 2008 The production "Sanningen om Marika" is a rare example of a production that combines traditional broadcast culture with the participative culture fostered primarily within the larp community in the Nordic countries.
Waern, Annika,, Denward, Marie,
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Fifth Issue Editorial: Exploring Access & Accessibility in Analog Role-Playing Games
本誌2024年号の発刊の趣旨は，アナログ・ロールプレイングゲームにおける「アクセス」と「アクセシビリティ」という相互に関連するテーマへと読者を導くものである．構造的な障壁や社会的偏見を浮き彫りにすることで，編集者たちは，ゲームにおける周縁化された人々や少数派のグループに対する包摂性の促進の重要性を強調している．本趣旨では，普遍主義的な「アクセス」のアプローチを超えることの必要性を訴え，多様なニーズ―例えばジェンダー，人種，社会経済的背景，障害など―を考慮した適応的な枠組みの重要性を説いている．学術的 ...
カム, ビョーン＝オーレ +1 more
core +1 more source
A Table-Top Role-Playing Game (TTRPG) for Developing Higher Education Employability Skills
, 2023 Employability provision in Higher Education is traditionally delivered in-curricula and adapted to the values and skills sets of programmes. In addition, extra-curricula & co-curricular employability activities are often available on demand to students.
Turner, I., Robinson, L.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Computer game playing and social skills: a pilot study
, 2010 Computer game playing is a popular leisure activity. However, there is little known about the longer-term effects that regular computer game playing could have on social development.
Griffiths, MD
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