Results 91 to 100 of about 585,725 (296)

The Panalba Role Playing Case [PDF]

open access: yes
The Panalba Role Playing Case was designed to get participants to examine their behavior in a situation where their role can lead them to act in a socially irresponsible manner.
JS Armstrong
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Strategies for Implementing Change: An Experiential Approach [PDF]

open access: yes
An attitude survey and a role-playing case were used to identify the typical approaches people use to implement important changes in organizations. This typical strategy, suggested or used by over 90% of the subjects, was not successful in producing ...
JS Armstrong
core  

Teaching Substantive Environmental Law and Practice Skills Through Interest Group Role-Playing [PDF]

open access: yes, 2016
Most law students take their first introductory course in environmental law during their second year of law school. The traditional first-year curriculum does little to prepare students for the complex statutory and regulatory models for most ...
Coplan, Karl S.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Keefektifan Layanan Bimbingan Kelompok Melalui Teknik Role Playing untuk Mengurangi Perilaku Bulliying

open access: yesEdukasia, 2023
The existence of bullying behavior in schools is certainly a scourge for educational units. With this research, namely applying the role playing method to class VII students at TanjungBalai 4 Public Middle School for the 2023-2024 academic year, this ...
Stariah, Ahmad Syarqawi
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Penerapan model pembelajaran role playing pada mata pelajaran aqidah akhlak di Kelas VIII MTs Muslimat NU Palangka Raya [PDF]

open access: yes, 2016
Latar belakang masalah mengapa peneliti ingin meneliti mengenai penerapan model pembelajaran role playing pada mata pelajaran aqidah akhlak ialah karena metode dan model pembelajaran yang digunakan guru bersifat konvensional yaitu satu arah (berpusat ...
Sylvia, Sylvia
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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