Results 181 to 190 of about 2,152,289 (358)

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

open access: yesCytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook   +2 more
wiley   +1 more source

Quantitative X‐Ray Fluorescence Imaging to Evaluate the Efficacy of Micro‐Structured Cellulose Foams and Poultices in Wall Painting Desalination

open access: yesChemistry–Methods, EarlyView.
This work assesses, through a quantitative micro energy dispersive X‐ray fluorescence imaging, the effective use of micro‐structured cellulose foams as a sustainable alternative to traditional poultices for desalinating fresco paintings. Foams were between 6 and 10 times more efficient, achieving rapid and in‐depth salt removal with reusability and ...
Martina Romani   +8 more
wiley   +1 more source

Sports cardiology in Europe from the ancient Greek-Roman era to the present

open access: yesEuropean Heart Journal, 2022
Silvia Castelletti   +2 more
openaire   +4 more sources

Cannabidiol Lacks Direct Effect on Cortical Excitability: A Randomized, Double Blind, Placebo Controlled, 3‐Way Crossover Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cannabidiol (CBD) is approved as an adjunctive treatment of seizures associated with Dravet syndrome, Lennox–Gastaut Syndrome, and tuberous sclerosis. Its therapeutic and adverse effects are thought to arise, at least partly, from a pharmacokinetic interaction with clobazam, another anti‐seizure medication (ASM).
Andriy A. Gorbenko   +7 more
wiley   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel   +13 more
wiley   +1 more source

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