Results 111 to 120 of about 4,100,373 (296)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Stability of serum proteins at room temperature

Bioingeniøren, 2013
Diagnostic laboratories require knowledge of the stability of various sample components to assess sample quality. A significant proportion of patient samples are sent by post.
Mari Myren Skårvold, Thea Berg, Mari Meslo Lien, Eli Kjøbli   +3 more
doaj  

Room temperature ferroelectricity in fluoroperovskite thin films

Scientific Reports, 2017
The NaMnF3 fluoride-perovskite has been found, theoretically, to be ferroelectric under epitaxial strain becoming a promising alternative to conventional oxides for multiferroic applications.
Ming Yang, Amit KC, A. C. Garcia-Castro, Pavel Borisov, E. Bousquet, David Lederman, Aldo H. Romero, Cheng Cen   +7 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Room temperature molecular up conversion in solution

Nature Communications, 2016
Up conversion is an Anti-Stokes luminescent process by which photons of low energy are piled up to generate light at a higher energy. Here, the authors report a supramolecular assembly of fluoride-bridged erbium complexes which exhibit this behaviour in ...
Aline Nonat, Chi Fai Chan, Tao Liu, Carlos Platas-Iglesias, Zhenyu Liu, Wing-Tak Wong, Wai-Kwok Wong, Ka-Leung Wong, Loïc J. Charbonnière   +8 more
doaj   +1 more source

Room-Temperature Superconductivity

, 2006
This is the first book on the subject of room-temperature superconductivity. The main purpose of the book is twofold. First, to show that, under suitable conditions, superconductivity can occur above room temperature. Secondly, to present general guidelines on how to synthesize a room temperature superconductor.
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Comparison and Prospect of Magnetic Heat Pump Cycle and Magnetic Refrigeration Cycle

Zhileng xuebao
As one of the main application directions of magnetocaloric effect near room temperature, room temperature magnetic heat pump has the characteristics of high efficiency, environmental protection, low noise and low vibration.
许戈耀, 张尧康, 余浩贤, 陈富城, 胡旭龙, 巫江虹   +5 more
doaj   +2 more sources

Room Temperature InGaAs/AlGaAsSb Single Photon Avalanche Diode

IEEE Photonics Journal
Near-infrared Single Photon Avalanche Diodes (SPADs) are the dominant, practical single photon detectors for quantum applications and low-level optical sensing.
J. Taylor-Mew, L. Li, T. Blain, C. H. Tan, J. S. Ng   +4 more
doaj   +1 more source