Results 51 to 60 of about 30,775 (302)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Contrast Participation Model and the Traditional Model Rooming-in Care of Neonatal Care
Journal of Nursing, 2015 <p>Contrast of the participation model and the traditional model of care in rooming effect of neonatal care. <strong>Methods:</strong> 114 cases of early maternal care group to tradition who admitted in our hospital from January 2014 to June 2014 were treated using the traditional way of nursing care.
Hadley Almond Kurban, Qingyan Wang
openaire +2 more sources
Pharmacological and non-pharmacological treatments for the Neonatal Abstinence Syndrome (NAS). [PDF]
, 2019 Neonatal abstinence syndrome is defined by signs and symptoms of withdrawal that infants develop after intrauterine maternal drug exposure. All infants with documented in utero opioid exposure, or a high pre-test probability of exposure should have ...
Kraft, W. K. +2 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
216 Jewish Hospital of St. Louis [PDF]
, 1967 https://digitalcommons.wustl.edu/bjc_216/1084/thumbnail ...
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Breast Feeding Initial Difficulties -descriptive study
Online Brazilian Journal of Nursing, 2006 This study aimed at identifying initial difficulties in breastfeeding in a rooming-in care. An assessment of ninety newly-born`sucking was carried out, using UNICEF standard protocol. Observation revealed that most mother-infant pairs presented favorable
Eunice Francisca Martins E. F. Martins +1 more
doaj
Trials, 2023 Background Despite the benefits of breastfeeding, early weaning is a reality, so less than 50% of children worldwide and in Brazil are on exclusive breastfeeding in the sixth month of life.
Mariana Torreglosa Ruiz +13 more
doaj +1 more source
Putting Families First: How the Opioid Epidemic is Affecting Children and Families, and the Child Welfare Policy Options to Address It [PDF]
, 2019 : Opioids and Child Welfare Across the country, placements in foster care are rising. In 2016, the U.S. Department of Health and Human Services reported that 273,539 children in the U.S. entered foster care.
American Academy of Pediatrics Council on Foster Care, Adoption, and Kinship Care +3 more
core +1 more source