Results 41 to 50 of about 295,445 (314)
Espacio, Tiempo y Forma. Serie V, Historia Contemporánea, 1991 En apariencia la cuestión referente a las relaciones entre FDR y Franco puede ser resuelta de una manera muy simple: sus ideales políticos eran radicalmente antitéticos, incluso en cierta manera más antitéticos que los de Rooseveit y Mussolini, por ...
Javier Tusell Gómez
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
‘A long, slow and painful road’: The Anglo-American alliance and the issue of cooperation with the USSR from Teheran to D-Day [PDF]
, 2012 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Taylor & Francis.The Second World War Anglo–American alliance was less cohesive on the political side than the military.
Folly, M
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Informative insights into the making of a president
Pacific Journalism Review, 2009 The Making of FDR argues that the image of US President Franklin Delano Roosevelt as a modern, charismatic, and politically astute leader was 'made' in a significant way by his talented but non-intellectual press secretary, Stephen Early.
Richard Shafer
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Male infant patient with a mesenteric cyst in the greater and lesser omenta: a case report
International Journal of Emergency Medicine, 2020 Background Mesenteric cysts are intra-abdominal masses of congenital origin, which most frequently occur in children, with an incidence of approximately 1 case per 20,000 pediatric admissions. Its progression can be asymptomatic, and its diagnosis can be
Rocio del Pilar Pereira-Ospina +5 more
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Revista de la Facultad de Medicina, 2016 Contexto: El Síndrome de Desgaste Laboral es un padecimiento que consiste en una respuesta prolongada de estrés en el organismo ante los factores estresantes emocionales e interpersonales que se presentan en el trabajo, que incluye: fatiga crónica ...
Natalia Ybarra +2 more
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Four Freedoms Park in Roosevelt Island, New York City [PDF]
, 2018 Il Memoriale delle Quattro Libertà è stato progettato nel 1973-1974 dall'architetto statunitense di origine lettone, Louis I. Kahn per la punta meridionale dell'isola Roosevelt a New York City, e fa parte di un parco commemorativo a Franklin D. Roosevelt.
Scatena, Donatella
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Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source