Results 41 to 50 of about 296,851 (313)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Exploring Lessons from Soviet Diplomacy and Western Allied Cooperation in World War II
Vestnik MGIMO-UniversitetaBased on an analysis of documentary sources from Russian, American, and British archives, this article delves into the intricacies of coalition diplomacy among the Allies during World War II. It places special emphasis on the adherence to obligations and
V. O. Pechatnov
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Espacio, Tiempo y Forma. Serie V, Historia Contemporánea, 1991 En apariencia la cuestión referente a las relaciones entre FDR y Franco puede ser resuelta de una manera muy simple: sus ideales políticos eran radicalmente antitéticos, incluso en cierta manera más antitéticos que los de Rooseveit y Mussolini, por ...
Javier Tusell Gómez
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Informative insights into the making of a president
Pacific Journalism Review, 2009 The Making of FDR argues that the image of US President Franklin Delano Roosevelt as a modern, charismatic, and politically astute leader was 'made' in a significant way by his talented but non-intellectual press secretary, Stephen Early.
Richard Shafer
doaj +1 more source
Male infant patient with a mesenteric cyst in the greater and lesser omenta: a case report
International Journal of Emergency Medicine, 2020 Background Mesenteric cysts are intra-abdominal masses of congenital origin, which most frequently occur in children, with an incidence of approximately 1 case per 20,000 pediatric admissions. Its progression can be asymptomatic, and its diagnosis can be
Rocio del Pilar Pereira-Ospina +5 more
doaj +1 more source
O sistema de notação musical na Antiguidade Clássica
Classica, Revista Brasileira de Estudos Clássicos, 2021 Neste texto apresento as informações básicas sobre a origem e o desenvolvimento do sistema de notação musical utilizado pelos músicos da Antiguidade greco-romana.
Roosevelt Rocha
doaj +1 more source
, 2012 Review of James Rusbridger, Betrayal at Pearl Harbour: How Churchill Lured Roosevelt into World War II and Bradley Smith Eric Nave: The Ultra-Magic Deals and the Most Secret Special Relationship, 1940 ...
Stafford, David
core +1 more source