Results 51 to 60 of about 298,662 (304)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Informative insights into the making of a president

Pacific Journalism Review, 2009
The Making of FDR argues that the image of US President Franklin Delano Roosevelt as a modern, charismatic, and politically astute leader was 'made' in a significant way by his talented but non-intellectual press secretary, Stephen Early.
Richard Shafer
doaj   +1 more source

O sistema de notação musical na Antiguidade Clássica

Classica, Revista Brasileira de Estudos Clássicos, 2021
Neste texto apresento as informações básicas sobre a origem e o desenvolvimento do sistema de notação musical utilizado pelos músicos da Antiguidade greco-romana.
Roosevelt Rocha
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Prevalencia del Síndrome de Desgaste Laboral en Residentes del Hospital Roosevelt y Hospital General San Juan de Dios en el año 2015

Revista de la Facultad de Medicina, 2016
Contexto: El Síndrome de Desgaste Laboral es un padecimiento que consiste en una respuesta prolongada de estrés en el organismo ante los factores estresantes emocionales e interpersonales que se presentan en el trabajo, que incluye: fatiga crónica ...
Natalia Ybarra, Jorge Guillermo Puente Rosal, Jorge García   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Entre ciência e aventura: considerações em torno da Expedição Roosevelt-Rondon

Fronteiras, 2016
O presente texto procura fazer um balanço dos resultados da Expedição Roosevelt-Rondon, a propósito do seu centenário lembrado recentemente. Evidencia que Roosevelt oscila entre ideias de preservação e o prazer das caçadas, apontando, também,
João Klug
doaj  

“Tuvimos que permanecer neutrales”: los Roosevelt y la cuestión de la ayuda a la República española durante la Guerra Civil (1936-1939)

Cuadernos de Historia de España
Este artículo analiza qué tipo de ayuda brindaron Franklin D. Roosevelt y Eleanor Roosevelt a la población civil y al Gobierno republicano durante la Guerra Civil española (1936 -1939), teniendo en cuenta la decisión que había tomado el Gobierno ...
María Luz Arroyo Vázquez
doaj   +1 more source

The President as International Leader [PDF]

, 1956
In this thesis, we address issues associated with programming modern heterogeneous systems while focusing on a special kind of heterogeneous systems that include multicore CPUs and one or more GPUs, called GPU-based systems.We consider the skeleton ...
Longaker, Richard P.
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source