Results 81 to 90 of about 3,586,110 (304)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Regulating root structure of potted lettuce to magnify absorption from APP and UAN fertilizers

Frontiers in Plant Science
IntroductionImprovement of root architecture is crucial to increasing nutrient acquisition.MethodsTwo pot experiments were conducted to investigate the effects of different concentrations of urea ammonium nitrate solution (UAN) and ammonium polyphosphate
Changqing Li, Changqing Li, Yahao Li, Yahao Li, Jungang Yang, Bingrui Lian, Jiqing Wang, Guoyuan Zou   +7 more
doaj   +1 more source

Integrated analysis of potential microbial consortia, soil nutritional status, and agro-climatic datasets to modulate P nutrient uptake and yield effectiveness of wheat under climate change resilience

Frontiers in Plant Science, 2023
Climate change has a devastating effect on wheat production; therefore, crop production might decline by 2030. Phosphorus (P) nutrient deficiency is another main limiting factor of reduced yield.
Mahreen Yahya, Maria Rasul, Maria Rasul, Sayed Zajif Hussain, Adil Dilawar, Adil Dilawar, Midrar Ullah, Lubna Rajput, Aftab Afzal, Muhammad Asif, Tesfaye Wubet, Tesfaye Wubet, Sumera Yasmin   +12 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Appropriate nitrogen application enhances saponin synthesis and growth mediated by optimizing root nutrient uptake ability

Journal of Ginseng Research, 2020
Background: Cultivation of medicinal crops, which synthesize hundreds of substances for curative functions, was focused on the synthesis of secondary metabolites rather than biomass accumulation. Nutrition is an important restrict factor for plant growth
Wei Wei, Chen Ye, Hui-Chuan Huang, Min Yang, Xin-Yue Mei, Fei Du, Xia-Hong He, Shu-Sheng Zhu, Yi-Xiang Liu   +8 more
doaj   +1 more source

Feedbacks between soil penetration resistance, root architecture and water uptake limit water accessibility and crop growth - A vicious circle.

Science of the Total Environment, 2018
Water is the most limiting resource for global crop production. The projected increase of dry spells due to climate change will further increase the problem of water limited crop yields.
T. Colombi, L. C. Torres, A. Walter, T. Keller   +3 more
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Blue Light Regulates Phosphate Deficiency-Dependent Primary Root Growth Inhibition in Arabidopsis

Frontiers in Plant Science, 2020
Plants have evolved mechanisms to improve utilization efficiency or acquisition of inorganic phosphate (Pi) in response to Pi deficiency, such as altering root architecture, secreting acid phosphatases, and activating the expression of genes related to ...
Chuan-Ming Yeh, Chuan-Ming Yeh, Chuan-Ming Yeh, Koichi Kobayashi, Sho Fujii, Hidehiro Fukaki, Nobutaka Mitsuda, Masaru Ohme-Takagi, Masaru Ohme-Takagi   +8 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source