Results 121 to 130 of about 178,289 (369)

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Apical extrusion of debris during root canal preparation using a novel nickel-titanium file system: WaveOne gold

Journal of Conservative Dentistry, 2017
Aim: This study was intended to evaluate the amount of apically extruded debris following root canal preparation with three different instrumentation systems.
A. Dinçer, M. Guneser, D. Arslan
semanticscholar   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

Canal Transportation and Centering Ability of ProTaper and SafeSider in Preparation of Curved Root Canals: A CBCT Evaluation [PDF]

, 2018
Introduction: Maintaining the original central canal path is an important parameter in efficient root canal preparation. Instruments causing minimal changes in original canal path are preferred for this purpose.
Abbasi, Mansoure, Bakhtiar, Hengameh, Delgoshayi, Negar, Ellini, Mohammad Reza, Ghannad, Setareh, Sakhdari, Shirin   +5 more
core   +2 more sources

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source

Research progress on the middle mesial root canal in the mandibular molar

口腔疾病防治, 2018
Of the various root canal morphologies in mandibular molars, the middle mesial root canal is located be⁃ tween the mesiobuccal root canal and the mesiolingual root canal.
ZHANG Bosen, WU Jiayuan
doaj   +1 more source

A micro-computed tomographic evaluation of dentinal microcrack alterations during root canal preparation using single-file Ni-Ti systems

Experimental and Therapeutic Medicine, 2017
The aim of the present study was to evaluate the length of dentinal microcracks observed prior to and following root canal preparation with different single-file nickel-titanium (Ni-Ti) systems using micro-computed tomography (micro-CT) analysis. A total
Mei-Lin Li, Weili Liao, Huaxiong Cai
semanticscholar   +1 more source

A study of root canal preparation using engine-driven root canal instruments in maxillary lateral incisor [PDF]

, 2016
日本歯科大学201
永島 万里子
core  

Evaluation of Canal Transportation and Centering Ability of RaCe and Af f-one Systems by Cone-beam Computed Tomography: An in Vitro Study [PDF]

Introduction Rotary systems have made significant advances to improve their root canal preparation efficacy. These instruments can properly preserve the root canal anatomy and morphology.
Abedi, Atefeh, Behrouzpour , Elham, Haghighat , Pouya, Mokhtari , Hadi, Rahimi , Saeed, Razi , Sedigheh   +5 more
core   +2 more sources

Concurrent Effects of Bleaching Materials and the Size of Root Canal Preparation on Cervical Dentin Microhardness [PDF]

, 2017
Introduction: The aim of the present study was to evaluate the concurrent effect of root canal preparation size and intra coronal bleaching on dentin microhardness.
Azad, Shaghayegh, Farahat, Farnaz, Kazemipoor, Maryam   +2 more
core   +2 more sources