Results 71 to 80 of about 1,201,448 (290)

Physicochemical, cytotoxicity, and biological properties of calcium silicate-based root canal sealers: A literature review

open access: yesSaudi Endodontic Journal, 2020
The aim of this study was to evaluate the main calcium silicate-based root canal sealers (bioceramic-based root canal sealers) currently used in endodontic field as well as their specific characteristics and to compare with other conventional sealers.
Abdelhamied Y Saad
doaj   +1 more source

Solubility of root canal sealers with different organic solvents

open access: yes, 2008
Objective. The aim of this study was to assess the solubility of the new root canal sealer Epiphany and to compare it with 2 conventional sealers against 2 organic solvents commonly used in ...
Bodrumlu, Emre   +5 more
core   +1 more source

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

open access: yesAdvanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang   +18 more
wiley   +1 more source

In vitro cytotoxicity analysis of bioceramic root canal sealers on human gingival fibroblast cells [PDF]

open access: yes, 2021
Cytotoxicity of various bioceramic root canal sealers are not well understood due to the limited scientific data. Previous research focused on comparing the conventional and bioceramic root canal sealers but there was no comparison between the latter ...
Ichwan, Solachuddin J. A.   +2 more
core   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

Clinical and radiographic outcome of a bioceramic sealer compared to a resin-based sealer: a retrospective study

open access: yesScientific Reports
Effective sealing of root canal systems is paramount in achieving favorable and enduring prognosis of root canal treatments (RCTs). Root canal sealers play a pivotal role in sealing the canal system.
Hamzah Ahmad Bani-Younes   +3 more
doaj   +1 more source

NCLX Inhibition plus Ca2+ Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Chuanbing Zhao   +7 more
wiley   +1 more source

The Characteristics of Tumor Microenvironment by the Single Cell Profile in Endometrial Cancer of no Specific Molecular Profile (NSMP) Subtype

open access: yesAdvanced Science, EarlyView.
A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan   +5 more
wiley   +1 more source

['تقییم مقارن لقدرة الختم القمی لسدادة قناة الجذر', 'Comparative Assessment of Root Canal Sealer’s Apical Sealing Ability']

open access: yesAl-Rafidain Dental Journal, 2022
.05) Conclusions: In this study, no experimented root canal sealer had perfect sealing ability. The experimental root canal sealers were similar in their sealing ability at apical area of root canal.]]>
Nur Alalaf, ِِEmad F Alkhalidi
doaj  

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

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