Engineering Highly Cellularized Living Materials via Mechanical Agitation
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani+9 more
wiley +1 more source
Understanding the Dynamics of Inflammatory Cytokines in Endodontic Diagnosis: A Systematic Review
The primary aim of this literature review is to delineate the key inflammatory cytokines involved in the pathophysiology of pulp inflammation. By elucidating the roles of these cytokines, a deeper comprehension of the distinct stages of inflamed pulp can
Ignacio Barbero-Navarro+5 more
doaj +1 more source
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
wiley +1 more source
Endodontic management of mandibular premolars with three root canals: Case series
The proper knowledge of both the external and internal anatomy of teeth is mandatory for adequate root canal treatment. Permanent mandibular premolars are usually single rooted with single root canal.
Yousef Hamad Al-Dahman+3 more
doaj +1 more source
Device to Deliver Endodontic Material for Temporary Dental Fillings [PDF]
Root canal therapy requires patients be treated over several visits to clean and shape the pulp chamber. In endodontic treatments, cotton wool is placed beneath the temporary filling to preserve the space of the pulp chamber and to prevent any blockage ...
Cyprus, Garrett N.+3 more
core +1 more source
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi+10 more
wiley +1 more source
Evaluation of sealing ability of chemically softened gutta-percha technique [PDF]
Introduction. Obturation of the root canal is the final phase of endodontic therapy and it is usually used to assess the quality of endodontic treatment.
Arbutina Radmila+4 more
core +1 more source
How to improve root canal filling in teeth subjected to radiation therapy for cancer.
The aim of this study was to evaluate the influence of radiation therapy on root canal sealer push-out bond strength (BS) to dentin and the sealer/dentin interface after different final irrigation solutions (NaOCl, EDTA, and chitosan).
Fabiana de Góes Paiola+6 more
semanticscholar +1 more source
Seeing inside the Body Using Wearable Sensing and Imaging Technologies
This review explores wearable technologies for noninvasive internal health monitoring. It categorizes approaches into indirect sensing (e.g., bioelectrical and biochemical signals) and direct imaging (e.g., wearable ultrasound and EIT), highlighting multimodal integration and system‐level innovation toward personalized, continuous healthcare.
Sumin Kim+3 more
wiley +1 more source
Treatment Rate Of Second Mesio-Buccal Canals In Maxillary Molars In A Musod Endodontic Resident Patient Population [PDF]
Purpose: The primary reason for non-surgical root canal treatment (NSRCT) failure in an upper molar is inadequate cleaning, shaping and filling of the second mesio-buccal root canal (MB2). Failure to locate and treat a present MB2 will lead to a worsened
Margel, Ryan Yale
core +1 more source