Results 101 to 110 of about 64,469 (311)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Tratamento da superfície externa da raiz no reimplante dental tardio [PDF]

open access: yes, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Após a avulsão dental, o dente deve ser reimplantado sempre que possível. Se o reimplante ocorrer 1 hora ou mais depois da avulsão, e se o dente permanecer
Ferreira, Roberta Varela
core  

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

Inter-appointment medication with calcium hydroxide in routine cases of root canal therapy

open access: yes, 2015
This chapter discusses the use of an inter-appointment application of calcium hydroxide in the endodontic treatment of teeth with apical periodontitis, from a historic and evidence-based perspective.
Bergenholtz, Gunnar,   +2 more
core  

Management Of Perforation And Separated Instrument Retrieval In The #36

open access: yesInternational Dental Journal
Introduction: In this case report, we repaired a perforation in the bottom of the left mandibular first permanent molar under a microscope, followed by the removal of a separated endodontic instrument with ultrasound assistance.
惠寒 黄, Huihan Huang
doaj   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

open access: yesAdvanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield   +13 more
wiley   +1 more source

Cigarette Smoking Increases the Risk of Root Canal Treatment

open access: yes, 2006
Few studies have investigated smoking as a risk factor for root canal treatment. We studied the effect of smoking on the incidence of root canal treatment, controlling for recognized risk factors, in 811 dentate male participants in the VA Dental ...
Garcia, C.   +5 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Efeito da ativação ultrassônica de soluções irrigadoras sobre a remoção da lama dentinária [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2014.O objetivo deste estudo foi avaliar, longitudinal e quantitativamente por meio de microscópio ...
Schmidt, Tamer Ferreira
core  

Single visit root canal treatment: Review

open access: yes, 2012
The main objective of performing root canal therapy is to eliminate bacteria from the infected root canal system or remove inflamed pulp tissue and close it with a biologically acceptable filling material.
Mothanna Al-Rahabi   +1 more
core   +1 more source

Home - About - Disclaimer - Privacy