Results 131 to 140 of about 169,948 (309)

Three-dimensional CBCT analysis of bone remodeling, root resorption, and incisive canal morphology during miniscrew-assisted aligner-based incisor retraction with and without extractions

Frontiers in Oral Health
ObjectivesThis study aimed to investigate three-dimensional changes in incisive canal (IC) morphology, root–canal proximity, and root resorption following maxillary incisor (U1) retraction with clear aligners, comparing extraction and non-extraction ...
Remsh Khaled Al-Rokhami, Remsh Khaled Al-Rokhami, Zhihua Li, Deguo Gao, Xin Zhao, Jingke Liu, Hua Fan, Karim Ahmed Sakran   +7 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source

Microscopic Retreatment Of Mandibular Molar With C-Shaped Canal Configuration

International Dental Journal
Introduction: C-shaped root canals predominantly occur in the mandibular second permanent molars, characterized by their C-shaped cross-sectional anatomy.
Ruyue Wang, Lina Wang, Ao Lu, jinyue Hu, Qing Sun   +4 more
doaj   +1 more source

Pengaruh Konsentrasi Ekstrak Etanol Daun Salam (Syzygium Polyanthum) Terhadap Hambatan Pertumbuhan Bakteri Enterococcus Faecalis Dominan di Saluran Akar In Vitro [PDF]

, 2015
Enterococcus faecalis is a Gram-positive anaerobic bacteria which usually found on periapical lesion. It is known as phatogenic bacteria often cause failure on root canal treatment. Herbs usage as an antibacterial agent has been widely applied by people,
, drg. Mahmud Kholifa, MDSc, , drg. SE Yuletnawati, MDSc, Saputri, Tiara Eka   +2 more
core  

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

Advanced Science, EarlyView.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang, Yaodong Gu, Wen Du, Lin Xie, Jinwei Quan, Yu Zhao, Ye Cheng, Zhaonan Wei, Yuanyuan Sha, Yi Wang, Dechao Xu, Xiang Gao, Min Chen, Xiangchen Gu   +13 more
wiley   +1 more source

NUP85 Mediates Endoplasmic Reticulum Stress through the USP47/ASK1 Signaling Pathway to Regulate the Progression of Liver Fibrosis

Advanced Science, EarlyView.
In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang, Haoran Yang, Linxin Pan, Chang Tian, Fucheng Zuo, Shilei Huang, Xianrui Li, Ming Chen, Cheng Qian, Jie Wang, Zhaolin Chen, Tao Xu   +11 more
wiley   +1 more source

Predictors of apical periodontitis in root canal treated teeth from an adult Nepalese subpopulation: a cross-sectional study

BMC Oral Health
Background Endodontic literature search revealed that no study has been conducted to evaluate the prevalence of apical periodontitis (AP) in root canal treated teeth from an adult Nepalese population of Madhesh Province.
Md. Asdaq Hussain, Shailendra Kumar Singh, Shazia Naz, Merazul Haque, Harish Kumar Shah, Abanish Singh   +5 more
doaj   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Treatment Rate Of Second Mesio-Buccal Canals In Maxillary Molars In A Musod Endodontic Resident Patient Population [PDF]

, 2013
Purpose: The primary reason for non-surgical root canal treatment (NSRCT) failure in an upper molar is inadequate cleaning, shaping and filling of the second mesio-buccal root canal (MB2). Failure to locate and treat a present MB2 will lead to a worsened
Margel, Ryan Yale
core   +1 more source