Results 41 to 50 of about 4,749 (216)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

C-SHAPED CONFIGURATION OF THE ROOT CANAL SYSTEM – PROBLEMS AND SOLUTIONS. [PDF]

open access: yesJournal of IMAB, 2014
Introduction: The patients with C-shaped configuration of the root canal system are definitely a problem in the everyday dental practice. The C-shaped configuration of the root canal can be seen in the mandibular and maxillary molars.
Janet Kirilova   +1 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Negotiating and Treating Lateral Canals: A Report of 7 Cases

open access: yesEuropean Endodontic Journal
This is a series of 7 cases in which the operator penetrated lateral canals with instruments. Two teeth present-ed with irreversible pulpitis, 4 with necrotic pulps, and 1 with previous treatment.
Luis F. Jiménez-rojas   +9 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Research progress on the middle mesial root canal in the mandibular molar

open access: yes口腔疾病防治, 2018
Of the various root canal morphologies in mandibular molars, the middle mesial root canal is located be⁃ tween the mesiobuccal root canal and the mesiolingual root canal.
ZHANG Bosen, WU Jiayuan
doaj   +1 more source

Electrocapillary Modulated Interfacial Tension Amplifies Liquid Metal Transduction

open access: yesAdvanced Functional Materials, EarlyView.
This study presented an electrocapillary‐enhanced magnetohydrodynamic pumping strategy that harnesses the Lorentz force and interfacial tension modulation of liquid metal droplets to achieve amplified fluidic power. The system enabled low‐voltage, self‐oscillating fluidic transduction with enhanced pressure and flow generation, supporting compact ...
Saba Firouznia   +3 more
wiley   +1 more source

PENATALAKSANAAN GIGI PREMOLAR KEDUA MAKSILA DENGAN SALURAN AKAR VERTUCCI TIPE V - laporan Kasus

open access: yesODONTO: Dental Journal, 2014
Background: The aim of the case report is to demonstrate the importance of knowing the root canals configuration in the maxillary second premolars. Maxillary second premolars usually have one root canal, however in several cases there is more than one ...
Arlina Nurhapsari
doaj   +1 more source

Coordinated Architectural and Chemical Reinforcement in the Crushing Mandible of a Soldier Termite

open access: yesAdvanced Functional Materials, EarlyView.
The crushing mandible of a soldier termite withstands substantial biting loads despite lacking mineral. Its cuticle is partitioned: convex teeth pair hardness and zinc enrichment with aligned chitin fibers for contact durability, while stiffer concave regions between teeth carry bending loads.
Andrew Tran Nguyen   +16 more
wiley   +1 more source

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