Results 61 to 70 of about 420,905 (352)

Green discoloration of the crown after internal root resorption treatment with grey mineral trioxide aggregate (MTA) [PDF]

open access: yes, 2011
Root resorption (RR) is the loss of dental hard tissues as a result of clastic activities. Internal inflammatory root resorption (IRR) is a type of RR characterized by progressive loss of tooth substance starting from the root canal wall.
Alonso Ezpeleta, Luis Oscar   +4 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

C-SHAPED CONFIGURATION OF THE ROOT CANAL SYSTEM – PROBLEMS AND SOLUTIONS. [PDF]

open access: yesJournal of IMAB, 2014
Introduction: The patients with C-shaped configuration of the root canal system are definitely a problem in the everyday dental practice. The C-shaped configuration of the root canal can be seen in the mandibular and maxillary molars.
Janet Kirilova   +1 more
doaj   +1 more source

A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health.

open access: yes, 2011
AIM: To investigate the probability of and factors influencing periapical status of teeth following primary (1°RCTx) or secondary (2°RCTx) root canal treatment.
Gulabivala, K, Mann, V, Ng, Y-L
core   +1 more source

Endodontic therapy of pathological resorptions of tooth root [PDF]

open access: yes, 2004
Pathological resorptions of a tooth root very often represent both a diagnostic and therapeutical problem. The goal of this study was, based on clinical research on a number of pathological resorptions of various types and localization in relation to ...
Opačić-Galić Vanja   +1 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Research progress on the middle mesial root canal in the mandibular molar

open access: yes口腔疾病防治, 2018
Of the various root canal morphologies in mandibular molars, the middle mesial root canal is located be⁃ tween the mesiobuccal root canal and the mesiolingual root canal.
ZHANG Bosen, WU Jiayuan
doaj   +1 more source

Expert consensus on irrigation and intracanal medication in root canal therapy

open access: yesInternational Journal of Oral Science
Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear.
Xiaoying Zou   +27 more
semanticscholar   +1 more source

Outcomes of Primary Endodontic Therapy in Medicaid Enrollees [PDF]

open access: yes, 2020
The objective of this study was to determine factors affecting survival of teeth after nonsurgical root canal therapy (NSRCT) among enrollees of Wisconsin Medicaid during the years 2001-2009.
Gainey, Timothy
core   +1 more source

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