Results 151 to 160 of about 1,671,483 (282)

The associated factors of root cause analysis of incident reporting in public primary healthcare in Malaysia. [PDF]

Sci Rep
Rani HA, Ismail A, Rahman HIA, Sani NARM.   +3 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Improved bayesian network with graph attention and prior algorithm for aircraft engine fault root cause analysis. [PDF]

Sci Rep
Yuan L, Han G, Dong P.
europepmc   +1 more source

Team experiences of the root cause analysis process after a sentinel event: a qualitative case study. [PDF]

BMC Health Serv Res, 2023
Liepelt S, Sundal H, Kirchhoff R.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Post-endoscopy esophageal adenocarcinoma and root cause analysis in Auckland, New Zealand. [PDF]

Endosc Int Open
Shin S, Kang D, Walmsley RS.
europepmc   +1 more source

Integrating the root cause analysis to machine learning interpretation for predicting future failure. [PDF]

Heliyon, 2023
Aditiyawarman T, Soedarsono JW, Setiawan Kaban AP, Suryadi, Rahmadani H, Riastuti R.   +5 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Root cause analysis of accidents and examining their interrelations from the perspective of workers, supervisors, and safety officers. [PDF]

PLoS One
Molamehdizadeh N, Halvani GH, Ebrahimi H, Farshad AA, Kharghani Moghadam SM, Eskandari T.   +5 more
europepmc   +1 more source

Monitoring and Root Cause Analysis of Clinical Biochemistry Turnaround Time at a Tertiary Care Institute. [PDF]

Cureus, 2023
Prasad P, Kumar R, Kumar S, Sinha P.
europepmc   +1 more source