Results 71 to 80 of about 1,671,483 (282)
Psychiatric outpatients flow and waiting time improvement using PDSA and RCA techniques
Payesh, 2016 Objective (s): Waits and delays are symptoms of disrupted patient flow that has a negative effect on patient satisfaction, staff retention and referrals.
Seyedeh Hamideh Ghazimirsaeid +1 more
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Patterns of unexpected in-hospital deaths: a root cause analysis
Patient Safety in Surgery, 2011 Background Respiratory alarm monitoring and rapid response team alerts on hospital general floors are based on detection of simple numeric threshold breaches.
Curry J Paul, Lynn Lawrence A
doaj +1 more source
Investigation of a CubeSat in Orbit Anomaly through Verification on Ground
Aerospace, 2020 Given the role of Cubesats in the new space economy, a statistically relevant number of CubeSats have flown, and considering the high percentage of failed missions, the investigation of in-orbit anomalies becomes of paramount importance.
Fabrizio Stesina, Sabrina Corpino
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Techniques for Root Cause Analysis [PDF]
Baylor University Medical Center Proceedings, 2001 The Joint Commission on Accreditation of Healthcare Organizations has begun requiring root cause analyses for all sentinel events. These analyses can be of enormous value. They capture both the big-picture perspective and the details. They facilitate system evaluation, analysis of need for corrective action, and tracking and trending.
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Teaching Root Cause Analysis Using Simulation: Curriculum and Outcomes
Journal of Medical Education and Curricular Development, 2019 Background: Clinicians are key drivers for improving health care quality and safety. However, some may lack experience in quality improvement and patient safety (QI/PS) methodologies, including root cause analysis (RCA).
Maya Aboumrad +2 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source