Results 91 to 100 of about 7,285,916 (251)
Improving rice yield and nitrogen use efficiency (NUE) are crucial challenges for coordinating food production and environmental health. However, little is known about the physiological mechanisms underlying the synergistic effects of high yield and NUE ...
Guohui Li +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Saline soil significantly hinders crop growth potential, reducing grain yields. Applying maize (Zea mays L.) straw extract, rich in potassium ions (K+), in saline soil regions may help alleviate salt stress in wheat (Triticum aestivum L.) seedlings by ...
Changhai Shi +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Enhancing winter wheat yield in early spring relies on optimal soil temperature (ST) conditions and robust root systems, particularly in cold and dry areas.
Ameet Kumar +3 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Behaviour of Dickey-Fuller Unit Root Tests Under Trend Misspecification [PDF]
We analyse the case where a unit root test is based on a Dickey-Fuller regression whose only deterministic term is a fixed intercept. Suppose, however, as could well be the case, that the actual data generating process includes a broken linear trend.
Tae-Hwan Kim +2 more
core
A matrix with real characteristic roots
In this note we prove the conjecture of J. D. Hoffman and B . M. Axilrod that a matrix with these properties has only real cha,racteristic roots and that these characteristic roots lie between zero and twice the maximum diagonal element. The second statement is a direct consequence of the first and properties (1), (2), and (3) by the theorem of S ...
openaire +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

