Results 141 to 150 of about 529,159 (305)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Effects of Root–Root Interactions on the Physiological Characteristics of Haloxylon ammodendron Seedlings

open access: yesPlants
The root traits and response strategies of plants play crucial roles in mediating interactions between plant root systems. Current research on the role of root exudates as underground chemical signals mediating these interactions has focused mainly on ...
Huifang Yang   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Responses in root physiological characteristics of

open access: yes, 2016
We selected the submerged macrophyte Vallisneria natans (Lour.) Hara for investigating the effects of nutrient loadings (nitrogen (N)-phosphorus (P) in mg·L-1: (1) 0.5, 0.05; (2) 1.0, 0.1; (3) 5.0, 0.5; (4) 10.0, 1.0) on ...
L. Yao   +6 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Rooting Patterns and Aucubin Content in Plantago lanceolata

open access: yesAgriculture
Ribwort plantain (Plantago lanceolata L.) is expected to open up new crop cultivation perspectives in arable farming in order to significantly reduce nitrogen losses through leaching, N2O emissions and to increase resilience under drought conditions ...
Michal Pol   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The characteristic roots of a matrix: a correction

open access: yesDuke Mathematical Journal, 1956
In einer Arbeit von \textit{S.-M. Leng} [Duke Math. J. 19, 139--154 (1952; Zbl 0046.01201)] ist die in Theorem 5 behauptete Abschätzung des Wertevorrats (im genannten Referat: 3) falsch. Ebenfalls unrichtig sind die Angaben der Theoreme 8, 9 über die Gültigkeit des Gleichheitszeichens in der Abschätzung der Eigenwerte (im Referat: 4, 5).
openaire   +2 more sources

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