Results 91 to 100 of about 569,037 (334)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Point Matching Technique for Root Coverage Exposed by Visible Gingival Recession [PDF]
Journal of Clinical and Diagnostic Research, 2018 A new point matching technique as a viable and effective treatment option for coverage of root surface exposed by visible gingival recession was designed while avoiding the complications and complaints often associated with traditional grafting ...
Awadhesh Kumar Singh, Anurag Saxena
doaj +1 more source
The periosteum eversion technique for coverage of denuded root surface
Journal of Indian Society of Periodontology, 2015 The periosteum is highly cellular connective tissue with rich vascularity and regenerative potential, which make it suitable autogenous graft. The periosteum eversion technique utilized periosteum for coverage of denuded root surface. The purpose of this case report was to evaluate the periosteum eversion technique that involves a single surgical site,
Preeti Kiran, Awadhesh Kumar Singh
openaire +4 more sources
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Finding The Lazy Programmer's Bugs [PDF]
, 2011 Traditionally developers and testers created huge numbers of explicit tests, enumerating interesting cases, perhaps biased by what they believe to be the current boundary conditions of the function being tested. Or at least, they were supposed to.
Allwood, Tristan Oliver Richard +1 more
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Journal of Indian Society of Periodontology, 2016 Background: Gingival recession is a common condition and is more prevalent in smokers. It is widely believed that root coverage procedures in smokers result in less desirable outcome compared to nonsmokers', and there are few controlled studies in ...
Chini Doraswamy Dwarakanath +3 more
doaj +1 more source
Shape-based peak identification for ChIP-Seq [PDF]
, 2010 We present a new algorithm for the identification of bound regions from ChIP-seq experiments. Our method for identifying statistically significant peaks from read coverage is inspired by the notion of persistence in topological data analysis and provides
A Barski +27 more
core +7 more sources
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Treatment of Gingival Recession [PDF]
, 2010 Gingival recession is an intriguing and complex phenomenon. Recession frequently disturbs patients because of sensitivity and esthetics. Many surgical techniques have been introduced to treat gingival recession, including those involving autogenous ...
Badawi, Hala +2 more
core +1 more source