Results 61 to 70 of about 2,175,939 (301)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Treatment of lingual gingival recession on mandibular lateral incisor using minimally invasive full-thickness tunneling technique and subepithelial palatal connective tissue graft

Journal of Indian Society of Periodontology, 2021
Gingival recession on the lingual aspect of teeth may cause dentinal hypersensitivity problems in patients. Treatment of such recessions is not a regular procedure owing to its anatomical restraints, difficulty in isolation as well as lack of esthetic ...
Eiti Agrawal, Rahul Chopra, Nikhil Sharma   +2 more
doaj   +1 more source

A Critical Evaluation of Methods for Root Coverage [PDF]

Critical Reviews in Oral Biology & Medicine, 1996
Gingival recession is the exposure of root surfaces due to apical migration of the gingival tissue margins. Although it seldom results in tooth loss, marginal tissue recession is associated with thermal and tactile sensitivity, esthetic complaints, and a tendency toward root caries. This article reviews the current surgical procedures for the coverage
M, Goldstein, L, Brayer, Z, Schwartz
openaire   +2 more sources

The effect of enamel matrix derivatives on root coverage: a 12-month follow-up of a randomized clinical trial.

Brazilian Oral Research, 2019
Subepithelial connective tissue grafts (SCTGs) with a coronally advanced flap (CAF) are accepted as the gold standard for covering denuded root surfaces. In recent years, enamel matrix derivatives (EMDs) have been used for their regenerative potential in
Hacer Sahin Aydinyurt, Y. Tekin, A. S. Ertuğrul   +2 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Modified Approach of Double Papillae Laterally Positioned Flap Technique using Alloderm® for Root Coverage [PDF]

Journal of Clinical and Diagnostic Research, 2014
Cosmetic concern is on increase in dental patients these days resulting in more demand for periodontal plastic surgical procedures. Gingival recession is one of the common problems which impairs aesthetic and may result in hypersensitivity and increase ...
Chitra Agarwal, Pragya Purohit, Suresh Kumar Sharma, Aashish Sharma   +3 more
doaj   +1 more source

Microsurgery for root coverage: A systematic review.

Pakistan journal of medical sciences, 2015
To evaluate whether microsurgery gains better result in root coverage compared to conventional surgical techniques.A number of databases were searched to identify eligible studies from January 1992 to January 2015.number of sites exhibiting complete root coverage and patients' esthetic satisfaction.Four Randomized Clinical Trials (RCTs) fulfilled the ...
Kang, Jian, Meng, Shu, Li, Chunjie, Luo, Zhenhua, Guo, Shujuan, Wu, Yafei   +5 more
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Amnion and Chorion Allografts in Combination with Coronally Advanced Flap in the Treatment of Gingival Recession: A Clinical Study [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Guided tissue regeneration (GTR) based root coverage using different allograft membranes has been utilized to correct gingival recession defects with promising results.
Sonali Chakraborthy, Savita Sambashivaiah, Rithesh Kulal, Shivaprasad Bilchodmath   +3 more
doaj   +1 more source