Results 101 to 110 of about 686,040 (265)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A hydroponic system for facilitating observation of plant virus infection in roots

Plant Signaling & Behavior
Plant viruses usually spread from the infection site to upper young leaves through plant phloem along with the plant nutrient solution flow. To track the infection status of plant viruses in root systems, we established an independent and controllable ...
Guoliang Chen, Yuchen Lei, Haijuan Wang, Yan Lu, Hongyou Zhou, Mingmin Zhao   +5 more
doaj   +1 more source

Genome-Wide Analysis of the ABCB Family and Its Expression in Adventitious Root Development of Paeonia ostii

Horticulturae
Tree peony (Paeonia ostii T. Hong et J. X. Zhang) is an important medicinal and ornamental plant. It would be useful to propagate this plant in tissue culture, but it is difficult to induce root formation.
Wenqian Shang, Can Cui, Xi Liu, Weihao Meng, Yongjie Qiu, Yuke Sun, Yuxiao Shen, Weichao Liu, Zheng Wang, Songlin He, Yinglong Song, Liyun Shi   +11 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

SnapShot: Root Development

Cell, 2013
Wilson, Michael, Goh, Tatsuaki, Voß, Ute, Bishopp, Anthony, Péret, Benjamin, Bennett, Malcolm   +5 more
openaire   +2 more sources

Promoting Effects of Piriformospora indica on the Growth and Development of Asparagus (Asparagus officinalis L.) Seedlings

Plants
As an endophytic fungus, Piriformospora indica has attracted great attention for its plant growth- and stress resistance-promoting effects on various host plants. However, up until now, there have been no reports on its application in asparagus.
Jing Zhao, Ying Wang, Huixia Song, Chao Luo, Chunzhen Cheng, Liping Mao   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source