Results 131 to 140 of about 2,609,418 (308)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
PlantsAs an endophytic fungus, Piriformospora indica has attracted great attention for its plant growth- and stress resistance-promoting effects on various host plants. However, up until now, there have been no reports on its application in asparagus.
Jing Zhao +5 more
doaj +1 more source
Development of a high-throughput system for phenotyping rice roots traits [PDF]
, 2010 A CIRAD project (Orytage) involving NARES and IRC partners aims at developing an international phenotyping network for rice adaptations to drought and thermal stresses in the context of gene discovery and genetic mapping.
Audebert, Alain +4 more
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Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Development and implementation of preventive-maintenance practices in Nigerian industries.
, 2006 A methodology for the development of PM using the modern approaches of FMEA, root-cause analysis, and fault-tree analysis is presented. Applying PM leads to a cost reduction in maintenance and less overall energy expenditure.
Eti, Mark C. +2 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Inflation divergence within the SADC [PDF]
This study investigates the feasibility of a monetary union in the Southern African Development Community (SADC) by testing for inflation convergence for 11 members. Quarterly data over the period 1992:3 – 2001:4 are employed.
Jaunky Chandr Vishal
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Root architecture of two sorghum varieties differ than drought stress tolerance : [Abstract, P 7.17] [PDF]
, 2009 Root architecture of two sorghum varieties, fitted in #Durra race# and with different response in drought conditions, has been studied on hydroponic system, pot and in situ on field.
Chopart, Jean-Louis +2 more
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