Results 61 to 70 of about 400,396 (290)
Root hairs aid soil penetration by anchoring the root surface to pore walls [PDF]
, 2016 The physical role of root hairs in anchoring the root tip during soil penetration was examined. Experiments using a hairless maize mutant (Zea mays: rth3–3) and its wild-type counterpart measured the anchorage force between the primary root of maize and ...
A. Glyn Bengough +5 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Frontiers in Plant Science, 2019 Transcriptional networks are tightly controlled in plant development and stress responses. Alternative polyadenylation (APA) has been found to regulate gene expression under abiotic stress by increasing the heterogeneity at mRNA 3′-ends.
Jingyi Cao +10 more
doaj +1 more source
Microtubules guide root hair tip growth [PDF]
New Phytologist, 2005 SummaryThe ability to establish cell polarity is crucial to form and function of an individual cell. Polarity underlies critical processes during cell development, such as cell growth, cell division, cell differentiation and cell signalling. Interphase cytoplasmic microtubules in tip‐growing fission yeast cells have been shown to play a particularly ...
Sieberer, B. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Frontiers in Plant Science, 2016 Root hairs are tubular outgrowths that originate from epidermal cells. Exposure of Arabidopsis to cadmium (Cd) and arsenic [arsenite, As(III)] increases root hair density and length.
Ramin Bahmani +3 more
doaj +1 more source
Food for thought: how nutrients regulate root system architecture [PDF]
, 2017 The spatial arrangement of the plant root system (root system architecture, RSA) is very sensitive to edaphic and endogenous signals that report on the nutrient status of soil and plant.
Amtmann, Anna, Shahzad, Zaigham
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Frontiers in Plant Science, 2013 We previously showed that seedlings harboring mutations in genes encoding ARK1, an armadillo repeat-containing kinesin, or AGD1, a class 1 ARF-GAP, have root hairs that exhibit wavy/spiral growth and two tips originating from one initiation site.
Cheol-Min eYoo, Elison B. Blancaflor
doaj +1 more source
Filling the Gaps to Solve the Extensin Puzzle [PDF]
, 2018 Extensins (EXTs) are highly repetitive plant O-glycoproteins that require several post-translational modifications (PTMs) to become functional in plant cell walls.
Borassi, Cecilia +6 more
core +1 more source