Results 131 to 140 of about 52,281 (352)

Expression of Cell Cycle Genes During Sesbania rostrata Stem Nodule Development

Molecular Plant-Microbe Interactions, 1997
Upon infection of Sesbania rostrata with Azorhizobium caulinodans, nodules are formed on roots and stems. Stem nodules develop from abundantly distributed dormant root primordia.
Sofie Goormachtig, Marcio Alves-Ferreira, Marc Van Montagu, Gilbert Engler, Marcelle Holsters   +4 more
doaj   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

Hormone-modulated transcription factors orchestrating the root nodule symbiosis

Frontiers in Plant Science
Transcription factors play essential roles modulating gene expression during plant development and the adaptation to environmental cues through the control of morphogenetic programs.
Cristina Kirolinko, Milagros Yacullo, Flavio Blanco, María Eugenia Zanetti   +3 more
doaj   +1 more source

Regulators and Regulation of Legume Root Nodule Development [PDF]

, 2000
Jens Stougaard
openalex   +1 more source

Breaking the Toughness‐Stretchability Trade‐Off in Hydrogels with Dynamic Hydrogen Bonding

Advanced Science, EarlyView.
A novel nanocomposite hydrogel architecture overcomes the inherent conflict between toughness and stretchability by integrating uniformly dispersed aminopropyl‐hybrid‐phyllosilicate nanosheets within a polyacrylamide matrix. This design leverages a dynamic hydrogen‐bonding network to facilitate efficient energy dissipation and self‐recovery.
Yining Gao, Yong Tao, Roland J.‐M. Pellenq, Fazhou Wang   +3 more
wiley   +1 more source

Characterization of heavy metal-resistant rhizobia and non-rhizobia isolated from root nodules of Trifolium sp. in a lead and zinc mining area [PDF]

, 2023
Sarah Rahal, Belkis Menaa, Djamel Chekireb   +2 more
openalex   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Microbiome properties in the root nodules of Prosopis cineraria, a leguminous desert tree

Microbiology Spectrum
We conducted a comprehensive analysis of the total microbiome and transcriptionally active microbiome communities in the roots and root nodules of Prosopis cineraria, an important leguminous tree in arid regions of many Asian countries.
Rashid Ali, Srinivasa R. Chaluvadi, Xuewen Wang, Khaled M. Hazzouri, Naganeeswaran Sudalaimuthuasari, Mohammed Rafi, Mariam Al-Nuaimi, Shina Sasi, Eric Antepenko, Jeffrey L. Bennetzen, Khaled M. A. Amiri   +10 more
doaj   +1 more source

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source