Results 141 to 150 of about 52,281 (352)

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

Phytohormones and Morphogenesis of Root Nodules and Lateral Roots of a Legume Plant [PDF]

Journal of Stress Physiology & Biochemistry, 2018
Data on the physiological role of phytohormones (mainly cytokinin and auxin) in the initiation of cortical cell division of the root, in the formation of nodule primordium and in its further organogenesis are summarized.
A. K. Glyan’ko
doaj  

A functional relationship between leghaemoglobin and nitrogenase based on novel measurements of the two proteins in legume root nodules [PDF]

, 1995
Felix D. Dakora
openalex   +1 more source

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

Advanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong, Wei Song, Wencai Liu, Hui Xu, Yuhao Yu, Xinyue Yang, Haiyan Li, Yanlun Zhu, Yaohua He   +8 more
wiley   +1 more source

Ammonia (¹⁴C-Methylamine) Transport across the Bacteroid and Peribacteroid Membranes of Soybean Root Nodules [PDF]

, 1990
Michael K. Udvardi, David A. Day
openalex   +1 more source

Wearable Tailored Passive Radiative Cooling Textile for Flexible Electronic Integration

Advanced Science, EarlyView.
A scalable, additive‐free wearable tailored passive radiative cooling textile (WRCT) with hierarchically structured fibers delivers exceptional thermal management, combining >95% solar reflectance, 0.96 mid‐infrared emissivity, and ultralow thermal conductivity (0.041 W/m·K).
Lung Chow, Jianpeng Zhang, Zehua Peng, Denglin Ye, Binbin Zhang, Jian Li, Wooyoung Park, Chentao Du, Xingcan Huang, Chun Ki Yiu, Yuze Qiu, Jingkun Zhou, Zhenlin Chen, Yuyu Gao, Weibin Zhu, Pengcheng Wu, Guangyao Zhao, Qiang Zhang, Yuan Guo, Zuowei Sun, Zhan Shen, Shuaiqi Ren, Sang Min Won, Jiyu Li, Xinge Yu   +24 more
wiley   +1 more source

Root Isoflavonoid Response to Grafting between Wild-Type and Nodulation-Mutant Soybean Plants [PDF]

, 1991
Myeong‐Je Cho, James E. Harper
openalex   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source