Results 81 to 90 of about 94,991 (285)
Potential Expansion of Root Chicory Cultivation Areas in Chile
Root chicory (Cichorium intybus var. sativum) is a major source of inulin, a fiber with many dietary and medicinal uses. Chile is the only country outside Europe that produces inulin and is the third largest exporter worldwide.
Donna Cortez +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Reduction to Restriction Estimates near the Principal Root Jet
This chapter shows that one may reduce the desired Fourier restriction estimate to a piece Ssubscript Greek small letter psi of the surface S lying above a small, “horn-shaped” neighborhood Dsubscript Greek small letter psi of the principal root jet ψ ...
Isroil A. Ikromov, Detlef Müller
core +1 more source
Tomato is a valuable agricultural commodity widely used across Africa with the potential to contribute to food and nutritional security. However, its yield, quality, and profitability are hindered by several challenges. The study evaluated the impact of
Alex Williams Ayarna +10 more
doaj +1 more source
Physiological and antioxidant changes in sunflower seeds under water restriction
: Seed vigor may be determinant for field performance, especially under water restriction conditions. Sunflower is a crop subject to these conditions in the field and, therefore, the aim of this study was to evaluate the physiological and antioxidant ...
Thais de Castro Morais +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Localized Expression of Cathepsin B-like Sequences from Root Nodules of Pea (Pisum sativum)
Cathepsin B is an ancient family of eukaryotic cysteine proteases. We describe PsCat1, a plant cathepsin B-like transcript, identified as an expressed sequence in Rhizobium-induced, nitrogen-fixing root nodules of pea.
Jason L. Vincent +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

