Results 91 to 100 of about 1,809,946 (329)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Anatomy of Soft Tissues of the Spinal Canal [PDF]

open access: yes, 1999
Background and Objectives. Important issues regarding the spread of solutions in the epidural space and the anatomy of the site of action of spinal and epidural injections are unresolved.
Quinn, Hogan, Toth, Jeffrey M.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The functor of toric varieties associated with Weyl chambers and Losev-Manin moduli spaces

open access: yes, 2011
A root system $R$ of rank $n$ defines an $n$-dimensional smooth projective toric variety $X(R)$ associated with its fan of Weyl chambers. We give a simple description of the functor of $X(R)$ in terms of the root system $R$ and apply this result in the ...
Batyrev, Victor, Blume, Mark
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Effects of Epigallocatechin-3-gallate (EGCG) on the bond strength of fiber posts to Sodium hypochlorite (NaOCl) treated intraradicular dentin

open access: yesScientific Reports, 2017
This study was to evaluate the effect of Epigallocatechin-3-gallate (EGCG) on the bond strength of two adhesive systems to the Sodium hypochlorite (NaOCl) treated intraradicular dentin. The roots were accepted regular root canal treatments and post space
Hao-han Yu   +7 more
doaj   +1 more source

PERAWATAN GIGI P1 ATAS DENGAN PERCABANGAN DI SALURAN AKAR SEPERTIGA APEKS (LAPORAN KASUS)

open access: yesJournal of Dentistry Indonesia, 2015
This case study reviewed conventional root canal treatment of a maxillary root canal treatment which unexpectedly had a single canal with two foramens.
Anggraeni Anggraeni   +2 more
doaj   +1 more source

QUANTUM ANTI-DE SITTER SPACE AT ROOTS OF UNITY [PDF]

open access: yesInternational Journal of Modern Physics B, 2000
An algebra of functions on q-deformed Anti-de Sitter space [Formula: see text] with star-structure is defined for roots of unity, which is covariant under Uq(so(2, D-1)). The scalar fields have an intrinsic high-energy cutoff, and arise most naturally on products of the quantum AdS space with a classical sphere.
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A CBCT study on distolingual space of mandibular molars in adults with different sagittal skeletal patterns [PDF]

open access: yesKouqiang yixue
Objective To study the distolingual space of mandibular molars in adult patients with different sagittal skeletal patterns, and to analyze the main bony anatomical sites that restrict molar distalization, in order to provide guidance for the treatment ...
LI Zongfeng, SUN Lian, PAN Yongchu
doaj   +1 more source

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