Results 101 to 110 of about 438,665 (263)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Jixie chuandong, 2018 The stress concentration effect of surface topography plays an important role in the fatigue properties of gears. The quantitative analysis method of the effect of surface topography on gear fatigue performance is the basic work of an in-depth study of ...
He Di, Tang Jinyuan, Li Guowen, Zhou Wei
doaj
Assessment of the root surface temperature during the use of intracanal agitation systems: In vitro study. [PDF]
Braz Dent J, 2023 Fontanezi BS +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Erratum: Biocontrol activity of nonpathogenic strains of Fusarium oxysporum: colonization on the root surface to overcome nutritional competition. [PDF]
Front Microbiol, 2023 Frontiers Production Office.
europepmc +1 more source
Root Penetration of Smeared Soil Surfaces
Experimental Agriculture, 1970 SUMMARYWinter wheat seeds were grown on compressed soil (a) with and without smearing, (b) with surface horizontal or at 45°, and (c) with and without a sand cover. Germination was not affected. At a soil suction of 0·1 bar, root penetration of the horizontal surface was decreased by smearing and by absence of an overburden; on a surface of 45 ...
openaire +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
SEM Analysis of MTAD Efficacy for Smear Layer Removal from Periodontally Affected Root Surfaces
Frontiers in Dentistry, 2011 Objective: Biopure® MTAD (Dentsply Tulsa Dental, USA) has been developed as a final irrigant following root canal shaping to remove intracanal smear layer.
B. Houshmand +5 more
doaj
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source