Results 101 to 110 of about 17,906,384 (253)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Threshold stochastic unit root models [PDF]
This paper introduces a new class of stochastic unit root (STUR) processes, where the randomness of the autorregresive unit root is driven by a threshold variable.
Gonzalo, Jesús, Montesinos, Raquel
core +1 more source
【Objective】Grape, as an important cash crop widely cultivated in the world, is not only the core raw material for winemaking and the fresh food industry, but also one of the key pillars of China's agricultural industrial structure upgrading and rural ...
LIU Hongjun +6 more
doaj +1 more source
On-farm inoculants based on arbuscular mycorrhizal fungi on wheat performance [PDF]
The objective of this work was to evaluate whether the use of on-farm inoculants based on arbuscular mycorrhizal fungi (AMF) interferes with the agronomic performance of wheat cultivars. The following treatments were applied to cultivars TBIO Calibre and
Michele Fornari +5 more
doaj +1 more source
We show that a fundamental sandwich algebra has an analogue of a root system of a semisimple Lie algebra. This leads to an analogue of a Weyl group, which we study in another paper.
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Karakterizacija korenovog sistema biljaka primenom savremenih metoda fenotipizacije [PDF]
The traits of the root system enable the plant to react, adapt and develop in different environmental conditions. The architecture of the root system is a basic component of the productivity of plants and involves morphological, anatomical and ...
Prijic, Zeljana +4 more
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

