Results 91 to 100 of about 9,703,974 (249)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

root-project/root: Release v6-11/02

open access: yes, 2017
<p>This is a development release. We created it to expose to users part of the enourmous amount of new functionalities which have been integrated in ROOT and will be available in ROOT 6.12/00.
Bertrand Bellenot   +29 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Distinct water and phosphorus extraction patterns are key to maintaining the productivity of sorghum under drought and limited soil resources

open access: yesScientific Reports
Nutrient and water limitations contribute to yield losses in semi-arid regions. Therefore, crop rotations incorporating nitrogen-fixing legumes and drought-tolerant sorghum varieties offer a strategy to improve the utilization of scarce soil resources ...
Sara Loftus   +8 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Unit Root Model Selection [PDF]

open access: yes
Some limit properties for information based model selection criteria are given in the context of unit root evaluation and various assumptions about initial conditions. Allowing for a nonparametric short memory component, standard information criteria are
Peter C.B. Phillips
core  

The kiwifruit (Actinidia sp.) vine root system: Responses to vine manipulations [PDF]

open access: yes, 2012
The root system is a significant component of whole-plant biomass in kiwifruit vines and is likely to be a considerable carbohydrate sink. Seasonal trends in root growth were investigated to infer seasonal fluctuations in root carbohydrate demand.
Black, Marykate Z.
core  

Threshold stochastic unit root models [PDF]

open access: yes, 2002
This paper introduces a new class of stochastic unit root (STUR) processes, where the randomness of the autorregresive unit root is driven by a threshold variable.
Gonzalo, Jesús, Montesinos, Raquel
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The effect of amorphous silica on soil–plant–water relations in soils with contrasting textures

open access: yesScientific Reports
This study investigates how amorphous silica (ASi) influences soil–plant–water interactions in distinct soil textures. A sandy loam and silty clay soil were mixed with 0 and 2% ASi, and their impact on soil retention and soil hydraulic conductivity ...
Mohsen Zarebanadkouki   +4 more
doaj   +1 more source

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